Recombinant multi-species CaMKII/CAMK2A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CaMKII/CAMK2A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]
The Alternative Names of target: CAMK2A,CAMKA,CaM kinase II subunit alpha,CaMK-II subunit alpha,CaMKII,CaMKIINalpha,CaMKIIalpha,Calcium/calmodulin-dependent protein kinase type II subunit alpha,Camk2a,MRD53,MRT63,PK2CDD,PKCCD,mKIAA0968

Target products collectionGo to CaMKII/CAMK2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0241-Ag-1/ GM-Tg-hg-IP0241-Ag-2 Human CaMKII/CAMK2A protein Human
GM-Tg-rg-IP0241-Ag-1/ GM-Tg-rg-IP0241-Ag-2 Rat CaMKII/CAMK2A protein Rat
GM-Tg-mg-IP0241-Ag-1/ GM-Tg-mg-IP0241-Ag-2 Mouse CaMKII/CAMK2A protein Mouse
GM-Tg-cynog-IP0241-Ag-1/ GM-Tg-cynog-IP0241-Ag-2 Cynomolgus/Rhesus macaque CaMKII/CAMK2A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0241-Ag-1/ GM-Tg-felg-IP0241-Ag-2 Feline CaMKII/CAMK2A protein Feline
GM-Tg-cang-IP0241-Ag-1/ GM-Tg-cang-IP0241-Ag-2 Canine CaMKII/CAMK2A protein Canine
GM-Tg-bovg-IP0241-Ag-1/ GM-Tg-bovg-IP0241-Ag-2 Bovine CaMKII/CAMK2A protein Bovine
GM-Tg-equg-IP0241-Ag-1/ GM-Tg-equg-IP0241-Ag-2 Equine CaMKII/CAMK2A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0241-Ag-1/ GM-Tg-hg-IP0241-Ag-2; GM-Tg-rg-IP0241-Ag-1/ GM-Tg-rg-IP0241-Ag-2;
GM-Tg-mg-IP0241-Ag-1/ GM-Tg-mg-IP0241-Ag-2; GM-Tg-cynog-IP0241-Ag-1/ GM-Tg-cynog-IP0241-Ag-2;
GM-Tg-felg-IP0241-Ag-1/ GM-Tg-felg-IP0241-Ag-2; GM-Tg-cang-IP0241-Ag-1/ GM-Tg-cang-IP0241-Ag-2;
GM-Tg-bovg-IP0241-Ag-1/ GM-Tg-bovg-IP0241-Ag-2; GM-Tg-equg-IP0241-Ag-1/ GM-Tg-equg-IP0241-Ag-2
Products Name CaMKII/CAMK2A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CaMKII/CAMK2A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CaMKII/CAMK2A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.