Explore CaMKII/CAMK2A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]
| Target ID |
GM-IP0241
|
| Target Name |
CaMKII/CAMK2A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
815
|
| Gene ID |
100071654 (Equus caballus), 101084342 (Felis catus), 12322 (Mus musculus), 25400 (Rattus norvegicus)
530719 (Bos taurus), 612941 (Canis lupus familiaris), 710540 (Macaca mulatta), 815 (Homo sapiens)
|
| Target Alternative Names |
CAMK2A,CAMKA,CaM kinase II subunit alpha,CaMK-II subunit alpha,CaMKII,CaMKIINalpha,CaMKIIalpha,Calcium/calmodulin-dependent protein kinase type II subunit alpha,Camk2a,MRD53,MRT63,PK2CDD,PKCCD,mKIAA0968
|
| Uniprot Accession |
P11798,P11275,Q9UQM7
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
ErbB signaling pathway, Calcium signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, Adrenergic signaling in cardiomyocytes, Wnt signaling pathway, Axon guidance, Circadian entrainment, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Olfactory transduction, Inflammatory mediator regulation of TRP channels, Insulin secretion, GnRH signaling pathway, Melanogenesis, Oxytocin signaling pathway, Aldosterone synthesis and secretion, Cushing syndrome, Gastric acid secretion, Amphetamine addiction, Tuberculosis, Pathways in cancer, Proteoglycans in cancer, Glioma, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000019790, ENSMUSG00000024617, ENSBTAG00000020087, ENSCAFG00845007828, ENSMMUG00000011563, ENSG00000070808
|
| Target Classification |
Kinase
|
Pre-made viral vector of CaMKII/CAMK2A cDNA Clones/ORF Plasmid
CaMKII/CAMK2A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo815 | Pre-made Human CAMK2A/CAMKA/MRD53 siRNA oligo Duplex | 815 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25400 | Pre-made Rat Camk2a/PKCCD/PK2CDD siRNA oligo Duplex | 25400 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12322 | Pre-made Mouse Camk2a/CaMKII/mKIAA0968 siRNA oligo Duplex | 12322 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710540 | Pre-made Cynomolgus/Rhesus macaque CAMK2A siRNA oligo Duplex | 710540 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084342 | Pre-made Cat/Feline CAMK2A siRNA oligo Duplex | 101084342 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612941 | Pre-made Dog/Canine CAMK2A siRNA oligo Duplex | 612941 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530719 | Pre-made Bovines/Cattle CAMK2A siRNA oligo Duplex | 530719 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071654 | Pre-made Equine/Horse CAMK2A siRNA oligo Duplex | 100071654 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CaMKII/CAMK2A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0241-Ab | Human | Anti-Human CaMKII/CAMK2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0241-Ab | Rat | Anti-Rat CaMKII/CAMK2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0241-Ab | Mouse | Anti-Mouse CaMKII/CAMK2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0241-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CaMKII/CAMK2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0241-Ab | Cat/Feline | Anti-Cat/Feline CaMKII/CAMK2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0241-Ab | Dog/Canine | Anti-Dog/Canine CaMKII/CAMK2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0241-Ab | Bovines/Cattle | Anti-Bovines/Cattle CaMKII/CAMK2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0241-Ab | Equine/Horse | Anti-Equine/Horse CaMKII/CAMK2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CaMKII/CAMK2A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0241-Ag | Human | Human CaMKII/CAMK2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0241-Ag | Rat | Rat CaMKII/CAMK2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0241-Ag | Mouse | Mouse CaMKII/CAMK2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0241-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CaMKII/CAMK2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0241-Ag | Cat/Feline | Cat/Feline CaMKII/CAMK2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0241-Ag | Dog/Canine | Dog/Canine CaMKII/CAMK2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0241-Ag | Bovines/Cattle | Bovines/Cattle CaMKII/CAMK2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0241-Ag | Equine/Horse | Equine/Horse CaMKII/CAMK2A recombinant protein | Mammalian cell | Detail |
