Recombinant multi-species PCSK7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCSK7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes and plays a role in the regulation of iron metabolism. A t(11;14)(q23;q32) chromosome translocation associated with B-cell lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq, Feb 2014]
The Alternative Names of target: LPC,Lymphoma proprotein convertase,PC7,PC8,PCSK7,Pcsk7,Prohormone convertase 7,Proprotein convertase 7 (PC7),Proprotein convertase 8 (PC8,Proprotein convertase subtilisin/kexin type 7,SPC7,Subtilisin/kexin-like protease PC7,hPC8)

Target products collectionGo to PCSK7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0192-Ag-1/ GM-Tg-hg-IP0192-Ag-2 Human PCSK7 protein Human
GM-Tg-rg-IP0192-Ag-1/ GM-Tg-rg-IP0192-Ag-2 Rat PCSK7 protein Rat
GM-Tg-mg-IP0192-Ag-1/ GM-Tg-mg-IP0192-Ag-2 Mouse PCSK7 protein Mouse
GM-Tg-cynog-IP0192-Ag-1/ GM-Tg-cynog-IP0192-Ag-2 Cynomolgus/Rhesus macaque PCSK7 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0192-Ag-1/ GM-Tg-felg-IP0192-Ag-2 Feline PCSK7 protein Feline
GM-Tg-cang-IP0192-Ag-1/ GM-Tg-cang-IP0192-Ag-2 Canine PCSK7 protein Canine
GM-Tg-bovg-IP0192-Ag-1/ GM-Tg-bovg-IP0192-Ag-2 Bovine PCSK7 protein Bovine
GM-Tg-equg-IP0192-Ag-1/ GM-Tg-equg-IP0192-Ag-2 Equine PCSK7 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0192-Ag-1/ GM-Tg-hg-IP0192-Ag-2; GM-Tg-rg-IP0192-Ag-1/ GM-Tg-rg-IP0192-Ag-2;
GM-Tg-mg-IP0192-Ag-1/ GM-Tg-mg-IP0192-Ag-2; GM-Tg-cynog-IP0192-Ag-1/ GM-Tg-cynog-IP0192-Ag-2;
GM-Tg-felg-IP0192-Ag-1/ GM-Tg-felg-IP0192-Ag-2; GM-Tg-cang-IP0192-Ag-1/ GM-Tg-cang-IP0192-Ag-2;
GM-Tg-bovg-IP0192-Ag-1/ GM-Tg-bovg-IP0192-Ag-2; GM-Tg-equg-IP0192-Ag-1/ GM-Tg-equg-IP0192-Ag-2
Products Name PCSK7 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PCSK7
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCSK7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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