Recombinant multi-species TAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
The Alternative Names of target: ABC17,ABCB2,APT1,ATP-binding cassette sub-family B member 2,Abcb2,Antigen peptide transporter 1,Cim,D6S114E,Ham-1,Ham1,MHC1D1,MTP1,PSF-1,PSF1,Peptide supply factor 1,Peptide transporter PSF1 (PSF-1),Peptide transporter TAP1,Peptide transporter involved in antigen processing 1,RING4,Really interesting new gene 4 protein (RING4),TAP,TAP1,TAP1*0102N,TAP1N,Tap-1,Tap1,Tap2,Y3

Target products collectionGo to TAP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0187-Ag-1/ GM-Tg-hg-IP0187-Ag-2 Human TAP1 protein Human
GM-Tg-rg-IP0187-Ag-1/ GM-Tg-rg-IP0187-Ag-2 Rat TAP1 protein Rat
GM-Tg-mg-IP0187-Ag-1/ GM-Tg-mg-IP0187-Ag-2 Mouse TAP1 protein Mouse
GM-Tg-cynog-IP0187-Ag-1/ GM-Tg-cynog-IP0187-Ag-2 Cynomolgus/Rhesus macaque TAP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0187-Ag-1/ GM-Tg-felg-IP0187-Ag-2 Feline TAP1 protein Feline
GM-Tg-cang-IP0187-Ag-1/ GM-Tg-cang-IP0187-Ag-2 Canine TAP1 protein Canine
GM-Tg-bovg-IP0187-Ag-1/ GM-Tg-bovg-IP0187-Ag-2 Bovine TAP1 protein Bovine
GM-Tg-equg-IP0187-Ag-1/ GM-Tg-equg-IP0187-Ag-2 Equine TAP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0187-Ag-1/ GM-Tg-hg-IP0187-Ag-2; GM-Tg-rg-IP0187-Ag-1/ GM-Tg-rg-IP0187-Ag-2;
GM-Tg-mg-IP0187-Ag-1/ GM-Tg-mg-IP0187-Ag-2; GM-Tg-cynog-IP0187-Ag-1/ GM-Tg-cynog-IP0187-Ag-2;
GM-Tg-felg-IP0187-Ag-1/ GM-Tg-felg-IP0187-Ag-2; GM-Tg-cang-IP0187-Ag-1/ GM-Tg-cang-IP0187-Ag-2;
GM-Tg-bovg-IP0187-Ag-1/ GM-Tg-bovg-IP0187-Ag-2; GM-Tg-equg-IP0187-Ag-1/ GM-Tg-equg-IP0187-Ag-2
Products Name TAP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TAP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TAP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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