Recombinant multi-species PEMT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PEMT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012]
The Alternative Names of target: PEAMT,PEMPT,PEMT,PEMT2,PHOMETH,PLMT,PNMT,Pempt,Pempt2,Pemt,Phosphatidylethanolamine N-methyltransferase,Phospholipid methyltransferase (PLMT)

Target products collectionGo to PEMT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0167-Ag-1/ GM-Tg-hg-IP0167-Ag-2 Human PEMT protein Human
GM-Tg-rg-IP0167-Ag-1/ GM-Tg-rg-IP0167-Ag-2 Rat PEMT protein Rat
GM-Tg-mg-IP0167-Ag-1/ GM-Tg-mg-IP0167-Ag-2 Mouse PEMT protein Mouse
GM-Tg-cynog-IP0167-Ag-1/ GM-Tg-cynog-IP0167-Ag-2 Cynomolgus/Rhesus macaque PEMT protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0167-Ag-1/ GM-Tg-felg-IP0167-Ag-2 Feline PEMT protein Feline
GM-Tg-cang-IP0167-Ag-1/ GM-Tg-cang-IP0167-Ag-2 Canine PEMT protein Canine
GM-Tg-bovg-IP0167-Ag-1/ GM-Tg-bovg-IP0167-Ag-2 Bovine PEMT protein Bovine
GM-Tg-equg-IP0167-Ag-1/ GM-Tg-equg-IP0167-Ag-2 Equine PEMT protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0167-Ag-1/ GM-Tg-hg-IP0167-Ag-2; GM-Tg-rg-IP0167-Ag-1/ GM-Tg-rg-IP0167-Ag-2;
GM-Tg-mg-IP0167-Ag-1/ GM-Tg-mg-IP0167-Ag-2; GM-Tg-cynog-IP0167-Ag-1/ GM-Tg-cynog-IP0167-Ag-2;
GM-Tg-felg-IP0167-Ag-1/ GM-Tg-felg-IP0167-Ag-2; GM-Tg-cang-IP0167-Ag-1/ GM-Tg-cang-IP0167-Ag-2;
GM-Tg-bovg-IP0167-Ag-1/ GM-Tg-bovg-IP0167-Ag-2; GM-Tg-equg-IP0167-Ag-1/ GM-Tg-equg-IP0167-Ag-2
Products Name PEMT protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PEMT
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PEMT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.