Explore PEMT gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012]
| Target ID |
GM-IP0167
|
| Target Name |
PEMT
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10400
|
| Gene ID |
100050945 (Equus caballus), 101088035 (Felis catus), 10400 (Homo sapiens), 18618 (Mus musculus) 25511 (Rattus norvegicus), 360197 (Bos taurus), 479526 (Canis lupus familiaris), 699083 (Macaca mulatta)
|
| Target Alternative Names |
PEAMT,PEMPT,PEMT,PEMT2,PHOMETH,PLMT,PNMT,Pempt,Pempt2,Pemt,Phosphatidylethanolamine N-methyltransferase,Phospholipid methyltransferase (PLMT)
|
| Uniprot Accession |
Q9UBM1,Q61907,Q08388,Q7YRH6
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Glycerophospholipid metabolism
|
| Gene Ensembl |
ENSECAG00000020584, ENSG00000133027, ENSMUSG00000000301, ENSBTAG00000016432, ENSCAFG00845024010, ENSMMUG00000006495
|
Pre-made viral vector of PEMT cDNA Clones/ORF Plasmid
PEMT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10400 | Pre-made Human PEMT/PLMT/PNMT siRNA oligo Duplex | 10400 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25511 | Pre-made Rat Pemt/PLMT/Pempt siRNA oligo Duplex | 25511 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18618 | Pre-made Mouse Pemt/PLMT/PEAMT siRNA oligo Duplex | 18618 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699083 | Pre-made Cynomolgus/Rhesus macaque PEMT siRNA oligo Duplex | 699083 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088035 | Pre-made Cat/Feline PEMT siRNA oligo Duplex | 101088035 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479526 | Pre-made Dog/Canine PEMT siRNA oligo Duplex | 479526 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360197 | Pre-made Bovines/Cattle PEMT/PLMT siRNA oligo Duplex | 360197 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050945 | Pre-made Equine/Horse PEMT siRNA oligo Duplex | 100050945 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PEMT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0167-Ab | Human | Anti-Human PEMT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0167-Ab | Rat | Anti-Rat PEMT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0167-Ab | Mouse | Anti-Mouse PEMT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0167-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PEMT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0167-Ab | Cat/Feline | Anti-Cat/Feline PEMT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0167-Ab | Dog/Canine | Anti-Dog/Canine PEMT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0167-Ab | Bovines/Cattle | Anti-Bovines/Cattle PEMT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0167-Ab | Equine/Horse | Anti-Equine/Horse PEMT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PEMT recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0167-Ag | Human | Human PEMT recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0167-Ag | Rat | Rat PEMT recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0167-Ag | Mouse | Mouse PEMT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0167-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PEMT recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0167-Ag | Cat/Feline | Cat/Feline PEMT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0167-Ag | Dog/Canine | Dog/Canine PEMT recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0167-Ag | Bovines/Cattle | Bovines/Cattle PEMT recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0167-Ag | Equine/Horse | Equine/Horse PEMT recombinant protein | Mammalian cell | Detail |