Recombinant multi-species G6PC/G6PC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine G6PC/G6PC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]
The Alternative Names of target: G-6-Pase,G6PC,G6PC1,G6PT,G6Pase,G6Pase),G6pc,G6pc1,G6pt,GSD1,GSD1a,Glc-6-Pase,Glucose-6-phosphatase (G-6-Pase,Glucose-6-phosphatase alpha (G6Pase-alpha),Glucose-6-phosphatase catalytic subunit 1,Psme3
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0145-Ag-1/ GM-Tg-hg-IP0145-Ag-2 | Human G6PC/G6PC1 protein | Human |
| GM-Tg-rg-IP0145-Ag-1/ GM-Tg-rg-IP0145-Ag-2 | Rat G6PC/G6PC1 protein | Rat |
| GM-Tg-mg-IP0145-Ag-1/ GM-Tg-mg-IP0145-Ag-2 | Mouse G6PC/G6PC1 protein | Mouse |
| GM-Tg-cynog-IP0145-Ag-1/ GM-Tg-cynog-IP0145-Ag-2 | Cynomolgus/Rhesus macaque G6PC/G6PC1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0145-Ag-1/ GM-Tg-felg-IP0145-Ag-2 | Feline G6PC/G6PC1 protein | Feline |
| GM-Tg-cang-IP0145-Ag-1/ GM-Tg-cang-IP0145-Ag-2 | Canine G6PC/G6PC1 protein | Canine |
| GM-Tg-bovg-IP0145-Ag-1/ GM-Tg-bovg-IP0145-Ag-2 | Bovine G6PC/G6PC1 protein | Bovine |
| GM-Tg-equg-IP0145-Ag-1/ GM-Tg-equg-IP0145-Ag-2 | Equine G6PC/G6PC1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP0145-Ag-1/ GM-Tg-hg-IP0145-Ag-2;
GM-Tg-rg-IP0145-Ag-1/ GM-Tg-rg-IP0145-Ag-2;
GM-Tg-mg-IP0145-Ag-1/ GM-Tg-mg-IP0145-Ag-2; GM-Tg-cynog-IP0145-Ag-1/ GM-Tg-cynog-IP0145-Ag-2; GM-Tg-felg-IP0145-Ag-1/ GM-Tg-felg-IP0145-Ag-2; GM-Tg-cang-IP0145-Ag-1/ GM-Tg-cang-IP0145-Ag-2; GM-Tg-bovg-IP0145-Ag-1/ GM-Tg-bovg-IP0145-Ag-2; GM-Tg-equg-IP0145-Ag-1/ GM-Tg-equg-IP0145-Ag-2 |
| Products Name | G6PC/G6PC1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | G6PC/G6PC1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine G6PC/G6PC1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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Through
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been established as a paradigmatic
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myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.