Recombinant multi-species CFLAR/FLIP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CFLAR/FLIP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]
The Alternative Names of target: 2310024N18Rik,A430105C05Rik,CASH,CASP8 and FADD-like apoptosis regulator,CASP8AP1,CFLAR,CLARP,Cash,Caspase homolog (CASH),Caspase-eight-related protein (Casper),Caspase-like apoptosis regulatory protein (CLARP),Casper,Cellular FLICE-like inhibitory protein (c-FLIP),Cflar,FADD-like antiapoptotic molecule 1 (FLAME-1),FLAME,FLAME-1,FLAME1,FLIP,Flip,Gm9845,I-FLICE,Inhibitor of FLICE (I-FLICE),MACH-related inducer of toxicity (MRIT),MRIT,Usurpin,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS,c-Flip,cFLIP

Target products collectionGo to CFLAR/FLIP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0138-Ag-1/ GM-Tg-hg-IP0138-Ag-2 Human CFLAR/FLIP protein Human
GM-Tg-rg-IP0138-Ag-1/ GM-Tg-rg-IP0138-Ag-2 Rat CFLAR/FLIP protein Rat
GM-Tg-mg-IP0138-Ag-1/ GM-Tg-mg-IP0138-Ag-2 Mouse CFLAR/FLIP protein Mouse
GM-Tg-cynog-IP0138-Ag-1/ GM-Tg-cynog-IP0138-Ag-2 Cynomolgus/Rhesus macaque CFLAR/FLIP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0138-Ag-1/ GM-Tg-felg-IP0138-Ag-2 Feline CFLAR/FLIP protein Feline
GM-Tg-cang-IP0138-Ag-1/ GM-Tg-cang-IP0138-Ag-2 Canine CFLAR/FLIP protein Canine
GM-Tg-bovg-IP0138-Ag-1/ GM-Tg-bovg-IP0138-Ag-2 Bovine CFLAR/FLIP protein Bovine
GM-Tg-equg-IP0138-Ag-1/ GM-Tg-equg-IP0138-Ag-2 Equine CFLAR/FLIP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0138-Ag-1/ GM-Tg-hg-IP0138-Ag-2; GM-Tg-rg-IP0138-Ag-1/ GM-Tg-rg-IP0138-Ag-2;
GM-Tg-mg-IP0138-Ag-1/ GM-Tg-mg-IP0138-Ag-2; GM-Tg-cynog-IP0138-Ag-1/ GM-Tg-cynog-IP0138-Ag-2;
GM-Tg-felg-IP0138-Ag-1/ GM-Tg-felg-IP0138-Ag-2; GM-Tg-cang-IP0138-Ag-1/ GM-Tg-cang-IP0138-Ag-2;
GM-Tg-bovg-IP0138-Ag-1/ GM-Tg-bovg-IP0138-Ag-2; GM-Tg-equg-IP0138-Ag-1/ GM-Tg-equg-IP0138-Ag-2
Products Name CFLAR/FLIP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CFLAR/FLIP
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CFLAR/FLIP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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