Recombinant multi-species CLK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CDC-like kinase 4,CLK4,Clk4,Dual specificity protein kinase CLK4
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0135-Ag-1/ GM-Tg-hg-IP0135-Ag-2 | Human CLK4 protein | Human |
| GM-Tg-rg-IP0135-Ag-1/ GM-Tg-rg-IP0135-Ag-2 | Rat CLK4 protein | Rat |
| GM-Tg-mg-IP0135-Ag-1/ GM-Tg-mg-IP0135-Ag-2 | Mouse CLK4 protein | Mouse |
| GM-Tg-cynog-IP0135-Ag-1/ GM-Tg-cynog-IP0135-Ag-2 | Cynomolgus/Rhesus macaque CLK4 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0135-Ag-1/ GM-Tg-felg-IP0135-Ag-2 | Feline CLK4 protein | Feline |
| GM-Tg-cang-IP0135-Ag-1/ GM-Tg-cang-IP0135-Ag-2 | Canine CLK4 protein | Canine |
| GM-Tg-bovg-IP0135-Ag-1/ GM-Tg-bovg-IP0135-Ag-2 | Bovine CLK4 protein | Bovine |
| GM-Tg-equg-IP0135-Ag-1/ GM-Tg-equg-IP0135-Ag-2 | Equine CLK4 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP0135-Ag-1/ GM-Tg-hg-IP0135-Ag-2;
GM-Tg-rg-IP0135-Ag-1/ GM-Tg-rg-IP0135-Ag-2;
GM-Tg-mg-IP0135-Ag-1/ GM-Tg-mg-IP0135-Ag-2; GM-Tg-cynog-IP0135-Ag-1/ GM-Tg-cynog-IP0135-Ag-2; GM-Tg-felg-IP0135-Ag-1/ GM-Tg-felg-IP0135-Ag-2; GM-Tg-cang-IP0135-Ag-1/ GM-Tg-cang-IP0135-Ag-2; GM-Tg-bovg-IP0135-Ag-1/ GM-Tg-bovg-IP0135-Ag-2; GM-Tg-equg-IP0135-Ag-1/ GM-Tg-equg-IP0135-Ag-2 |
| Products Name | CLK4 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CLK4 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLK4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.