Recombinant multi-species CLK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CDC-like kinase 4,CLK4,Clk4,Dual specificity protein kinase CLK4

Target products collectionGo to CLK4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0135-Ag-1/ GM-Tg-hg-IP0135-Ag-2 Human CLK4 protein Human
GM-Tg-rg-IP0135-Ag-1/ GM-Tg-rg-IP0135-Ag-2 Rat CLK4 protein Rat
GM-Tg-mg-IP0135-Ag-1/ GM-Tg-mg-IP0135-Ag-2 Mouse CLK4 protein Mouse
GM-Tg-cynog-IP0135-Ag-1/ GM-Tg-cynog-IP0135-Ag-2 Cynomolgus/Rhesus macaque CLK4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0135-Ag-1/ GM-Tg-felg-IP0135-Ag-2 Feline CLK4 protein Feline
GM-Tg-cang-IP0135-Ag-1/ GM-Tg-cang-IP0135-Ag-2 Canine CLK4 protein Canine
GM-Tg-bovg-IP0135-Ag-1/ GM-Tg-bovg-IP0135-Ag-2 Bovine CLK4 protein Bovine
GM-Tg-equg-IP0135-Ag-1/ GM-Tg-equg-IP0135-Ag-2 Equine CLK4 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0135-Ag-1/ GM-Tg-hg-IP0135-Ag-2; GM-Tg-rg-IP0135-Ag-1/ GM-Tg-rg-IP0135-Ag-2;
GM-Tg-mg-IP0135-Ag-1/ GM-Tg-mg-IP0135-Ag-2; GM-Tg-cynog-IP0135-Ag-1/ GM-Tg-cynog-IP0135-Ag-2;
GM-Tg-felg-IP0135-Ag-1/ GM-Tg-felg-IP0135-Ag-2; GM-Tg-cang-IP0135-Ag-1/ GM-Tg-cang-IP0135-Ag-2;
GM-Tg-bovg-IP0135-Ag-1/ GM-Tg-bovg-IP0135-Ag-2; GM-Tg-equg-IP0135-Ag-1/ GM-Tg-equg-IP0135-Ag-2
Products Name CLK4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CLK4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLK4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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