Explore CLK4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0135
|
| Target Name |
CLK4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
57396
|
| Gene ID |
100058051 (Equus caballus), 101087897 (Felis catus), 12750 (Mus musculus), 287269 (Rattus norvegicus)
474645 (Canis lupus familiaris), 529633 (Bos taurus), 57396 (Homo sapiens), 702752 (Macaca mulatta)
|
| Target Alternative Names |
CDC-like kinase 4,CLK4,Clk4,Dual specificity protein kinase CLK4
|
| Uniprot Accession |
O35493,Q9HAZ1
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Legionellosis
|
| Gene Ensembl |
ENSECAG00000014153, ENSMUSG00000020385, ENSCAFG00845009410, ENSBTAG00000019414, ENSG00000113240, ENSMMUG00000004002
|
| Target Classification |
Kinase
|
CLK4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo57396 | Pre-made Human CLK4 siRNA oligo Duplex | 57396 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287269 | Pre-made Rat Clk4 siRNA oligo Duplex | 287269 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12750 | Pre-made Mouse Clk4 siRNA oligo Duplex | 12750 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702752 | Pre-made Cynomolgus/Rhesus macaque CLK4 siRNA oligo Duplex | 702752 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087897 | Pre-made Cat/Feline CLK4 siRNA oligo Duplex | 101087897 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474645 | Pre-made Dog/Canine CLK4 siRNA oligo Duplex | 474645 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo529633 | Pre-made Bovines/Cattle CLK4 siRNA oligo Duplex | 529633 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058051 | Pre-made Equine/Horse CLK4 siRNA oligo Duplex | 100058051 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CLK4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0135-Ab | Human | Anti-Human CLK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0135-Ab | Rat | Anti-Rat CLK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0135-Ab | Mouse | Anti-Mouse CLK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0135-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CLK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0135-Ab | Cat/Feline | Anti-Cat/Feline CLK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0135-Ab | Dog/Canine | Anti-Dog/Canine CLK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0135-Ab | Bovines/Cattle | Anti-Bovines/Cattle CLK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0135-Ab | Equine/Horse | Anti-Equine/Horse CLK4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CLK4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0135-Ag | Human | Human CLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0135-Ag | Rat | Rat CLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0135-Ag | Mouse | Mouse CLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0135-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0135-Ag | Cat/Feline | Cat/Feline CLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0135-Ag | Dog/Canine | Dog/Canine CLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0135-Ag | Bovines/Cattle | Bovines/Cattle CLK4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0135-Ag | Equine/Horse | Equine/Horse CLK4 recombinant protein | Mammalian cell | Detail |
