Recombinant multi-species AADAT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AADAT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
The Alternative Names of target: 2-aminoadipate aminotransferase,2-aminoadipate transaminase,AADAT,Aadat,Aadt,Alpha-aminoadipate aminotransferase (AadAT),Glycine transaminase AADAT,KAT/AadAT,KAT2,KATII,KYAT2,Kat2,Kyat2,Kynurenine aminotransferase II,Kynurenine--glyoxylate transaminase AADAT,Kynurenine--oxoglutarate aminotransferase II,Kynurenine--oxoglutarate transaminase 2,Kynurenine--oxoglutarate transaminase II,Kynurenine/alpha-aminoadipate aminotransferase,Methionine--glyoxylate transaminase AADAT,mKat-2,mitochondrial

Target products collectionGo to AADAT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0130-Ag-1/ GM-Tg-hg-IP0130-Ag-2 Human AADAT protein Human
GM-Tg-rg-IP0130-Ag-1/ GM-Tg-rg-IP0130-Ag-2 Rat AADAT protein Rat
GM-Tg-mg-IP0130-Ag-1/ GM-Tg-mg-IP0130-Ag-2 Mouse AADAT protein Mouse
GM-Tg-cynog-IP0130-Ag-1/ GM-Tg-cynog-IP0130-Ag-2 Cynomolgus/Rhesus macaque AADAT protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0130-Ag-1/ GM-Tg-felg-IP0130-Ag-2 Feline AADAT protein Feline
GM-Tg-cang-IP0130-Ag-1/ GM-Tg-cang-IP0130-Ag-2 Canine AADAT protein Canine
GM-Tg-bovg-IP0130-Ag-1/ GM-Tg-bovg-IP0130-Ag-2 Bovine AADAT protein Bovine
GM-Tg-equg-IP0130-Ag-1/ GM-Tg-equg-IP0130-Ag-2 Equine AADAT protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0130-Ag-1/ GM-Tg-hg-IP0130-Ag-2; GM-Tg-rg-IP0130-Ag-1/ GM-Tg-rg-IP0130-Ag-2;
GM-Tg-mg-IP0130-Ag-1/ GM-Tg-mg-IP0130-Ag-2; GM-Tg-cynog-IP0130-Ag-1/ GM-Tg-cynog-IP0130-Ag-2;
GM-Tg-felg-IP0130-Ag-1/ GM-Tg-felg-IP0130-Ag-2; GM-Tg-cang-IP0130-Ag-1/ GM-Tg-cang-IP0130-Ag-2;
GM-Tg-bovg-IP0130-Ag-1/ GM-Tg-bovg-IP0130-Ag-2; GM-Tg-equg-IP0130-Ag-1/ GM-Tg-equg-IP0130-Ag-2
Products Name AADAT protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AADAT
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AADAT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.