Explore AADAT gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
| Target ID |
GM-IP0130
|
| Target Name |
AADAT
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
51166
|
| Gene ID |
100067095 (Equus caballus), 101091616 (Felis catus), 23923 (Mus musculus), 29416 (Rattus norvegicus)
486059 (Canis lupus familiaris), 508929 (Bos taurus), 51166 (Homo sapiens), 695264 (Macaca mulatta)
|
| Target Alternative Names |
2-aminoadipate aminotransferase,2-aminoadipate transaminase,AADAT,Aadat,Aadt,Alpha-aminoadipate aminotransferase (AadAT),Glycine transaminase AADAT,KAT/AadAT,KAT2,KATII,KYAT2,Kat2,Kyat2,Kynurenine aminotransferase II,Kynurenine--glyoxylate transaminase AADAT,Kynurenine--oxoglutarate aminotransferase II,Kynurenine--oxoglutarate transaminase 2,Kynurenine--oxoglutarate transaminase II,Kynurenine/alpha-aminoadipate aminotransferase,Methionine--glyoxylate transaminase AADAT,mKat-2,mitochondrial
|
| Uniprot Accession |
Q9WVM8,Q64602,Q5E9N4,Q8N5Z0
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000013400, ENSMUSG00000057228, ENSCAFG00845028500, ENSBTAG00000050967, ENSG00000109576, ENSMMUG00000019473
|
| Target Classification |
|
AADAT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo51166 | Pre-made Human AADAT/KAT2/KATII siRNA oligo Duplex | 51166 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29416 | Pre-made Rat Aadat/Kat2 siRNA oligo Duplex | 29416 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo23923 | Pre-made Mouse Aadat/Aadt/Kat2 siRNA oligo Duplex | 23923 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695264 | Pre-made Cynomolgus/Rhesus macaque AADAT siRNA oligo Duplex | 695264 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091616 | Pre-made Cat/Feline AADAT siRNA oligo Duplex | 101091616 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486059 | Pre-made Dog/Canine AADAT siRNA oligo Duplex | 486059 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508929 | Pre-made Bovines/Cattle AADAT siRNA oligo Duplex | 508929 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067095 | Pre-made Equine/Horse AADAT siRNA oligo Duplex | 100067095 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AADAT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0130-Ab | Human | Anti-Human AADAT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0130-Ab | Rat | Anti-Rat AADAT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0130-Ab | Mouse | Anti-Mouse AADAT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0130-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AADAT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0130-Ab | Cat/Feline | Anti-Cat/Feline AADAT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0130-Ab | Dog/Canine | Anti-Dog/Canine AADAT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0130-Ab | Bovines/Cattle | Anti-Bovines/Cattle AADAT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0130-Ab | Equine/Horse | Anti-Equine/Horse AADAT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
AADAT recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0130-Ag | Human | Human AADAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0130-Ag | Rat | Rat AADAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0130-Ag | Mouse | Mouse AADAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0130-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AADAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0130-Ag | Cat/Feline | Cat/Feline AADAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0130-Ag | Dog/Canine | Dog/Canine AADAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0130-Ag | Bovines/Cattle | Bovines/Cattle AADAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0130-Ag | Equine/Horse | Equine/Horse AADAT recombinant protein | Mammalian cell | Detail |
