Recombinant multi-species PHGDH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PHGDH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]
The Alternative Names of target: 2-oxoglutarate reductase,3-PGDH,3PGDH,4930479N23,A10,D-3-phosphoglycerate dehydrogenase,HEL-S-113,Malate dehydrogenase,NLS,NLS1,PDG,PGAD,PGD,PGDH,PHGDH,PHGDHD,Phgdh,SERA

Target products collectionGo to PHGDH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0116-Ag-1/ GM-Tg-hg-IP0116-Ag-2 Human PHGDH protein Human
GM-Tg-rg-IP0116-Ag-1/ GM-Tg-rg-IP0116-Ag-2 Rat PHGDH protein Rat
GM-Tg-mg-IP0116-Ag-1/ GM-Tg-mg-IP0116-Ag-2 Mouse PHGDH protein Mouse
GM-Tg-cynog-IP0116-Ag-1/ GM-Tg-cynog-IP0116-Ag-2 Cynomolgus/Rhesus macaque PHGDH protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0116-Ag-1/ GM-Tg-felg-IP0116-Ag-2 Feline PHGDH protein Feline
GM-Tg-cang-IP0116-Ag-1/ GM-Tg-cang-IP0116-Ag-2 Canine PHGDH protein Canine
GM-Tg-bovg-IP0116-Ag-1/ GM-Tg-bovg-IP0116-Ag-2 Bovine PHGDH protein Bovine
GM-Tg-equg-IP0116-Ag-1/ GM-Tg-equg-IP0116-Ag-2 Equine PHGDH protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0116-Ag-1/ GM-Tg-hg-IP0116-Ag-2; GM-Tg-rg-IP0116-Ag-1/ GM-Tg-rg-IP0116-Ag-2;
GM-Tg-mg-IP0116-Ag-1/ GM-Tg-mg-IP0116-Ag-2; GM-Tg-cynog-IP0116-Ag-1/ GM-Tg-cynog-IP0116-Ag-2;
GM-Tg-felg-IP0116-Ag-1/ GM-Tg-felg-IP0116-Ag-2; GM-Tg-cang-IP0116-Ag-1/ GM-Tg-cang-IP0116-Ag-2;
GM-Tg-bovg-IP0116-Ag-1/ GM-Tg-bovg-IP0116-Ag-2; GM-Tg-equg-IP0116-Ag-1/ GM-Tg-equg-IP0116-Ag-2
Products Name PHGDH protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PHGDH
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PHGDH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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