PHGDH Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PHGDH gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]

Target ID GM-IP0116
Target Name PHGDH
Gene Group ldentifer
（Target Gene ID in Homo species) 		26227
Gene ID 100059940 (Equus caballus), 101088505 (Felis catus), 236539 (Mus musculus), 26227 (Homo sapiens)
505103 (Bos taurus), 58835 (Rattus norvegicus), 607890 (Canis lupus familiaris), 713480 (Macaca mulatta)
Target Alternative Names 2-oxoglutarate reductase,3-PGDH,3PGDH,4930479N23,A10,D-3-phosphoglycerate dehydrogenase,HEL-S-113,Malate dehydrogenase,NLS,NLS1,PDG,PGAD,PGD,PGDH,PHGDH,PHGDHD,Phgdh,SERA
Uniprot Accession Q61753,O43175,Q5EAD2,O08651
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease Breast Cancer
Disease from KEGG Metabolic pathways
Gene Ensembl ENSECAG00000005228, ENSMUSG00000053398, ENSG00000092621, ENSBTAG00000039719, ENSCAFG00845006590, ENSMMUG00000023089


Pre-made viral vector of PHGDH cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001113Human PHGDH/3-PGDH/3PGDH Lentivirus plasmidNM_006623.326227HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV001456Human PHGDH/3-PGDH/3PGDH Lentivirus plasmidNM_006623.426227HumanLentivirus plasmidmCherry3xflag (C-Terminal)CMVDetail
pGMLV001805Human PHGDH/3-PGDH/3PGDH Lentivirus plasmidNM_006623.326227HumanLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMPC004900Human PHGDH/3-PGDH/3PGDH Mammalian (Non-Viral Vector) plasmidNM_00662326227HumanMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLP001113Human PHGDH/3-PGDH/3PGDH Lentivirus particleNM_006623.326227HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001456Human PHGDH/3-PGDH/3PGDH Lentivirus particleNM_006623.426227HumanLentivirus particlemCherry3xflag (C-Terminal)CMVDetail
vGMLV001805Human PHGDH/3-PGDH/3PGDH Lentivirus particleNM_006623.326227HumanLentivirus particleNull3xflag (C-Terminal)CMVDetail
pGMAAV001218Mouse Phgdh/3-PGDH/3PGDH Adeno-associate virus(AAV) plasmidNM_016966.3236539MouseAdeno-associate virus(AAV) plasmidZsGreenNullSM22aDetail
pGMLPm002722Mouse Phgdh/3-PGDH/3PGDH Lentivirus plasmidNM_016966236539MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001218Mouse Phgdh/3-PGDH/3PGDH Adeno-associate virus(AAV) particleNM_016966.3236539MouseAdeno-associate virus(AAV) particleZsGreenNullSM22aDetail
vGMLPm002722Mouse Phgdh/3-PGDH/3PGDH Lentivirus particleNM_016966236539MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


PHGDH siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo26227Pre-made Human PHGDH/NLS/PDG siRNA oligo Duplex26227HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo58835Pre-made Rat Phgdh siRNA oligo Duplex58835RatIn-vitro grade; in-vivo gradeDetail
pGMoligo236539Pre-made Mouse Phgdh/A10/PGD siRNA oligo Duplex236539MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo713480Pre-made Cynomolgus/Rhesus macaque PHGDH siRNA oligo Duplex713480Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101088505Pre-made Cat/Feline PHGDH siRNA oligo Duplex101088505Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo607890Pre-made Dog/Canine PHGDH siRNA oligo Duplex607890Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo505103Pre-made Bovines/Cattle PHGDH siRNA oligo Duplex505103Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100059940Pre-made Equine/Horse PHGDH siRNA oligo Duplex100059940Equine/HorseIn-vitro grade; in-vivo gradeDetail


PHGDH antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-IP0116-AbHumanAnti-Human PHGDH monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-IP0116-AbRatAnti-Rat PHGDH monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-IP0116-AbMouseAnti-Mouse PHGDH monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-IP0116-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque PHGDH monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-IP0116-AbCat/FelineAnti-Cat/Feline PHGDH monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-IP0116-AbDog/CanineAnti-Dog/Canine PHGDH monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-IP0116-AbBovines/CattleAnti-Bovines/Cattle PHGDH monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-IP0116-AbEquine/HorseAnti-Equine/Horse PHGDH monoclonal antibodymabTherapeutics Target antibodyDetail


PHGDH recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-IP0116-AgHumanHuman PHGDH recombinant proteinMammalian cellDetail
GM-Tg-rg-IP0116-AgRatRat PHGDH recombinant proteinMammalian cellDetail
GM-Tg-mg-IP0116-AgMouseMouse PHGDH recombinant proteinMammalian cellDetail
GM-Tg-cynog-IP0116-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque PHGDH recombinant proteinMammalian cellDetail
GM-Tg-felg-IP0116-AgCat/FelineCat/Feline PHGDH recombinant proteinMammalian cellDetail
GM-Tg-cang-IP0116-AgDog/CanineDog/Canine PHGDH recombinant proteinMammalian cellDetail
GM-Tg-bovg-IP0116-AgBovines/CattleBovines/Cattle PHGDH recombinant proteinMammalian cellDetail
GM-Tg-equg-IP0116-AgEquine/HorseEquine/Horse PHGDH recombinant proteinMammalian cellDetail