Recombinant multi-species MKK7/MAP2K7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MKK7/MAP2K7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
The Alternative Names of target: 5930412N11Rik,Dual specificity mitogen-activated protein kinase kinase 7,JNK-activating kinase 2,JNKK,JNKK 2,JNKK 2),JNKK2,Jnkk2,MAP kinase kinase 7,MAP2K7,MAPK/ERK kinase 7 (MEK 7),MAPKK 7,MAPKK7,MEK,MEK 7,MKK7,Map2k7,Mapkk7,Mek7,Mkk7,PRKMK7,Prkmk7,SAPKK-4,SAPKK4,SAPKK4),Stress-activated protein kinase kinase 4 (SAPK kinase 4,c-Jun N-terminal kinase kinase 2 (JNK kinase 2,sek2

Target products collectionGo to MKK7/MAP2K7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0114-Ag-1/ GM-Tg-hg-IP0114-Ag-2 Human MKK7/MAP2K7 protein Human
GM-Tg-rg-IP0114-Ag-1/ GM-Tg-rg-IP0114-Ag-2 Rat MKK7/MAP2K7 protein Rat
GM-Tg-mg-IP0114-Ag-1/ GM-Tg-mg-IP0114-Ag-2 Mouse MKK7/MAP2K7 protein Mouse
GM-Tg-cynog-IP0114-Ag-1/ GM-Tg-cynog-IP0114-Ag-2 Cynomolgus/Rhesus macaque MKK7/MAP2K7 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0114-Ag-1/ GM-Tg-felg-IP0114-Ag-2 Feline MKK7/MAP2K7 protein Feline
GM-Tg-cang-IP0114-Ag-1/ GM-Tg-cang-IP0114-Ag-2 Canine MKK7/MAP2K7 protein Canine
GM-Tg-bovg-IP0114-Ag-1/ GM-Tg-bovg-IP0114-Ag-2 Bovine MKK7/MAP2K7 protein Bovine
GM-Tg-equg-IP0114-Ag-1/ GM-Tg-equg-IP0114-Ag-2 Equine MKK7/MAP2K7 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0114-Ag-1/ GM-Tg-hg-IP0114-Ag-2; GM-Tg-rg-IP0114-Ag-1/ GM-Tg-rg-IP0114-Ag-2;
GM-Tg-mg-IP0114-Ag-1/ GM-Tg-mg-IP0114-Ag-2; GM-Tg-cynog-IP0114-Ag-1/ GM-Tg-cynog-IP0114-Ag-2;
GM-Tg-felg-IP0114-Ag-1/ GM-Tg-felg-IP0114-Ag-2; GM-Tg-cang-IP0114-Ag-1/ GM-Tg-cang-IP0114-Ag-2;
GM-Tg-bovg-IP0114-Ag-1/ GM-Tg-bovg-IP0114-Ag-2; GM-Tg-equg-IP0114-Ag-1/ GM-Tg-equg-IP0114-Ag-2
Products Name MKK7/MAP2K7 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MKK7/MAP2K7
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MKK7/MAP2K7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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