Recombinant multi-species GMPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GMPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 670032,GATD7,GMP synthase [glutamine-hydrolyzing],GMP synthetase,GMPS,Glutamine amidotransferase,Gm9479,Gmps

Target products collectionGo to GMPS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0108-Ag-1/ GM-Tg-hg-IP0108-Ag-2 Human GMPS protein Human
GM-Tg-rg-IP0108-Ag-1/ GM-Tg-rg-IP0108-Ag-2 Rat GMPS protein Rat
GM-Tg-mg-IP0108-Ag-1/ GM-Tg-mg-IP0108-Ag-2 Mouse GMPS protein Mouse
GM-Tg-cynog-IP0108-Ag-1/ GM-Tg-cynog-IP0108-Ag-2 Cynomolgus/Rhesus macaque GMPS protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0108-Ag-1/ GM-Tg-felg-IP0108-Ag-2 Feline GMPS protein Feline
GM-Tg-cang-IP0108-Ag-1/ GM-Tg-cang-IP0108-Ag-2 Canine GMPS protein Canine
GM-Tg-bovg-IP0108-Ag-1/ GM-Tg-bovg-IP0108-Ag-2 Bovine GMPS protein Bovine
GM-Tg-equg-IP0108-Ag-1/ GM-Tg-equg-IP0108-Ag-2 Equine GMPS protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0108-Ag-1/ GM-Tg-hg-IP0108-Ag-2; GM-Tg-rg-IP0108-Ag-1/ GM-Tg-rg-IP0108-Ag-2;
GM-Tg-mg-IP0108-Ag-1/ GM-Tg-mg-IP0108-Ag-2; GM-Tg-cynog-IP0108-Ag-1/ GM-Tg-cynog-IP0108-Ag-2;
GM-Tg-felg-IP0108-Ag-1/ GM-Tg-felg-IP0108-Ag-2; GM-Tg-cang-IP0108-Ag-1/ GM-Tg-cang-IP0108-Ag-2;
GM-Tg-bovg-IP0108-Ag-1/ GM-Tg-bovg-IP0108-Ag-2; GM-Tg-equg-IP0108-Ag-1/ GM-Tg-equg-IP0108-Ag-2
Products Name GMPS protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GMPS
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GMPS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.