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Target
sublocation: Introcelluar Protein.
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0108
|
| Target Name |
GMPS
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8833
|
| Gene ID |
100051936 (Equus caballus), 101088776 (Felis catus), 229363 (Mus musculus), 295088 (Rattus norvegicus) 477123 (Canis lupus familiaris), 511200 (Bos taurus), 706932 (Macaca mulatta), 8833 (Homo sapiens)
|
| Target Alternative Names |
670032,GATD7,GMP synthase [glutamine-hydrolyzing],GMP synthetase,GMPS,Glutamine amidotransferase,Gm9479,Gmps
|
| Uniprot Accession |
Q3THK7,Q4V7C6,P49915
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000023269, ENSMUSG00000027823, ENSCAFG00845021930, ENSBTAG00000013013, ENSMMUG00000007324, ENSG00000163655
|
GMPS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8833 | Pre-made Human GMPS/GATD7 siRNA oligo Duplex | 8833 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo295088 | Pre-made Rat Gmps siRNA oligo Duplex | 295088 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo229363 | Pre-made Mouse Gmps/670032/Gm9479 siRNA oligo Duplex | 229363 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706932 | Pre-made Cynomolgus/Rhesus macaque GMPS siRNA oligo Duplex | 706932 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088776 | Pre-made Cat/Feline GMPS siRNA oligo Duplex | 101088776 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477123 | Pre-made Dog/Canine GMPS siRNA oligo Duplex | 477123 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511200 | Pre-made Bovines/Cattle GMPS siRNA oligo Duplex | 511200 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051936 | Pre-made Equine/Horse GMPS siRNA oligo Duplex | 100051936 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GMPS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0108-Ab | Human | Anti-Human GMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0108-Ab | Rat | Anti-Rat GMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0108-Ab | Mouse | Anti-Mouse GMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0108-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0108-Ab | Cat/Feline | Anti-Cat/Feline GMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0108-Ab | Dog/Canine | Anti-Dog/Canine GMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0108-Ab | Bovines/Cattle | Anti-Bovines/Cattle GMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0108-Ab | Equine/Horse | Anti-Equine/Horse GMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GMPS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0108-Ag | Human | Human GMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0108-Ag | Rat | Rat GMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0108-Ag | Mouse | Mouse GMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0108-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0108-Ag | Cat/Feline | Cat/Feline GMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0108-Ag | Dog/Canine | Dog/Canine GMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0108-Ag | Bovines/Cattle | Bovines/Cattle GMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0108-Ag | Equine/Horse | Equine/Horse GMPS recombinant protein | Mammalian cell | Detail |