Recombinant multi-species MAPKAPK5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAPKAPK5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
The Alternative Names of target: MAP kinase-activated protein kinase 5,MAPK-activated protein kinase 5,MAPKAP kinase 5,MAPKAP-K5,MAPKAPK-5,MAPKAPK5,MK-5,MK5,Mapkapk5,NCFD,PRAK,p38-regulated/activated protein kinase (PRAK)

Target products collectionGo to MAPKAPK5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0100-Ag-1/ GM-Tg-hg-IP0100-Ag-2 Human MAPKAPK5 protein Human
GM-Tg-rg-IP0100-Ag-1/ GM-Tg-rg-IP0100-Ag-2 Rat MAPKAPK5 protein Rat
GM-Tg-mg-IP0100-Ag-1/ GM-Tg-mg-IP0100-Ag-2 Mouse MAPKAPK5 protein Mouse
GM-Tg-cynog-IP0100-Ag-1/ GM-Tg-cynog-IP0100-Ag-2 Cynomolgus/Rhesus macaque MAPKAPK5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0100-Ag-1/ GM-Tg-felg-IP0100-Ag-2 Feline MAPKAPK5 protein Feline
GM-Tg-cang-IP0100-Ag-1/ GM-Tg-cang-IP0100-Ag-2 Canine MAPKAPK5 protein Canine
GM-Tg-bovg-IP0100-Ag-1/ GM-Tg-bovg-IP0100-Ag-2 Bovine MAPKAPK5 protein Bovine
GM-Tg-equg-IP0100-Ag-1/ GM-Tg-equg-IP0100-Ag-2 Equine MAPKAPK5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0100-Ag-1/ GM-Tg-hg-IP0100-Ag-2; GM-Tg-rg-IP0100-Ag-1/ GM-Tg-rg-IP0100-Ag-2;
GM-Tg-mg-IP0100-Ag-1/ GM-Tg-mg-IP0100-Ag-2; GM-Tg-cynog-IP0100-Ag-1/ GM-Tg-cynog-IP0100-Ag-2;
GM-Tg-felg-IP0100-Ag-1/ GM-Tg-felg-IP0100-Ag-2; GM-Tg-cang-IP0100-Ag-1/ GM-Tg-cang-IP0100-Ag-2;
GM-Tg-bovg-IP0100-Ag-1/ GM-Tg-bovg-IP0100-Ag-2; GM-Tg-equg-IP0100-Ag-1/ GM-Tg-equg-IP0100-Ag-2
Products Name MAPKAPK5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MAPKAPK5
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAPKAPK5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.