Recombinant multi-species DLK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DLK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015]
The Alternative Names of target: DLK,DLK-1,DLK1,Delta1,Dlk1,DlkI,FA1,Ly107,PREF1,Peg9,Pref-1,Protein delta homolog 1,SCP1,ZOG,Zog,pG2,pref-1

Target products collectionGo to DLK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0084-Ag-1/ GM-Tg-hg-IP0084-Ag-2 Human DLK1 protein Human
GM-Tg-rg-IP0084-Ag-1/ GM-Tg-rg-IP0084-Ag-2 Rat DLK1 protein Rat
GM-Tg-mg-IP0084-Ag-1/ GM-Tg-mg-IP0084-Ag-2 Mouse DLK1 protein Mouse
GM-Tg-cynog-IP0084-Ag-1/ GM-Tg-cynog-IP0084-Ag-2 Cynomolgus/Rhesus macaque DLK1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0084-Ag-1/ GM-Tg-felg-IP0084-Ag-2 Feline DLK1 protein Feline
GM-Tg-cang-IP0084-Ag-1/ GM-Tg-cang-IP0084-Ag-2 Canine DLK1 protein Canine
GM-Tg-bovg-IP0084-Ag-1/ GM-Tg-bovg-IP0084-Ag-2 Bovine DLK1 protein Bovine
GM-Tg-equg-IP0084-Ag-1/ GM-Tg-equg-IP0084-Ag-2 Equine DLK1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0084-Ag-1/ GM-Tg-hg-IP0084-Ag-2; GM-Tg-rg-IP0084-Ag-1/ GM-Tg-rg-IP0084-Ag-2;
GM-Tg-mg-IP0084-Ag-1/ GM-Tg-mg-IP0084-Ag-2; GM-Tg-cynog-IP0084-Ag-1/ GM-Tg-cynog-IP0084-Ag-2;
GM-Tg-felg-IP0084-Ag-1/ GM-Tg-felg-IP0084-Ag-2; GM-Tg-cang-IP0084-Ag-1/ GM-Tg-cang-IP0084-Ag-2;
GM-Tg-bovg-IP0084-Ag-1/ GM-Tg-bovg-IP0084-Ag-2; GM-Tg-equg-IP0084-Ag-1/ GM-Tg-equg-IP0084-Ag-2
Products Name DLK1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DLK1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DLK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.