Explore DLK1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015]
| Target ID |
GM-IP0084
|
| Target Name |
DLK1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8788
|
| Gene ID |
100054933 (Equus caballus), 101081814 (Felis catus), 114587 (Rattus norvegicus), 13386 (Mus musculus) 281117 (Bos taurus), 490860 (Canis lupus familiaris), 707595 (Macaca mulatta), 8788 (Homo sapiens)
|
| Target Alternative Names |
DLK,DLK-1,DLK1,Delta1,Dlk1,DlkI,FA1,Ly107,PREF1,Peg9,Pref-1,Protein delta homolog 1,SCP1,ZOG,Zog,pG2,pref-1
|
| Uniprot Accession |
O70534,Q09163,P80370
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000029428, ENSMUSG00000040856, ENSCAFG00845004428, ENSMMUG00000020038, ENSG00000185559
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of DLK1 cDNA Clones/ORF Plasmid
DLK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8788 | Pre-made Human DLK1/DLK/FA1 siRNA oligo Duplex | 8788 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114587 | Pre-made Rat Dlk1/Zog/DLK-1 siRNA oligo Duplex | 114587 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13386 | Pre-made Mouse Dlk1/FA1/ZOG siRNA oligo Duplex | 13386 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707595 | Pre-made Cynomolgus/Rhesus macaque DLK1 siRNA oligo Duplex | 707595 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081814 | Pre-made Cat/Feline DLK1 siRNA oligo Duplex | 101081814 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490860 | Pre-made Dog/Canine DLK1 siRNA oligo Duplex | 490860 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281117 | Pre-made Bovines/Cattle DLK1 siRNA oligo Duplex | 281117 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054933 | Pre-made Equine/Horse DLK1 siRNA oligo Duplex | 100054933 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DLK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0084-Ab | Human | Anti-Human DLK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0084-Ab | Rat | Anti-Rat DLK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0084-Ab | Mouse | Anti-Mouse DLK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0084-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DLK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0084-Ab | Cat/Feline | Anti-Cat/Feline DLK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0084-Ab | Dog/Canine | Anti-Dog/Canine DLK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0084-Ab | Bovines/Cattle | Anti-Bovines/Cattle DLK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0084-Ab | Equine/Horse | Anti-Equine/Horse DLK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
DLK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0084-Ag | Human | Human DLK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0084-Ag | Rat | Rat DLK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0084-Ag | Mouse | Mouse DLK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0084-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DLK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0084-Ag | Cat/Feline | Cat/Feline DLK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0084-Ag | Dog/Canine | Dog/Canine DLK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0084-Ag | Bovines/Cattle | Bovines/Cattle DLK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0084-Ag | Equine/Horse | Equine/Horse DLK1 recombinant protein | Mammalian cell | Detail |