Recombinant multi-species FUT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FUT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Differences in the expression of this gene are associated with host susceptibility to viral infection. [provided by RefSeq, Aug 2020]
The Alternative Names of target: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3,4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase,Alpha-3-fucosyltransferase FUT3,Blood group Lewis alpha-4-fucosyltransferase (Lewis FT),CD174,FT3B,FUT3,FucT-III,Fucosyltransferase 3,Fucosyltransferase III (FucT-III),LE,Les
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0076-Ag-1/ GM-Tg-hg-IP0076-Ag-2 | Human FUT3 protein | Human |
| GM-Tg-rg-IP0076-Ag-1/ GM-Tg-rg-IP0076-Ag-2 | Rat FUT3 protein | Rat |
| GM-Tg-mg-IP0076-Ag-1/ GM-Tg-mg-IP0076-Ag-2 | Mouse FUT3 protein | Mouse |
| GM-Tg-cynog-IP0076-Ag-1/ GM-Tg-cynog-IP0076-Ag-2 | Cynomolgus/Rhesus macaque FUT3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0076-Ag-1/ GM-Tg-felg-IP0076-Ag-2 | Feline FUT3 protein | Feline |
| GM-Tg-cang-IP0076-Ag-1/ GM-Tg-cang-IP0076-Ag-2 | Canine FUT3 protein | Canine |
| GM-Tg-bovg-IP0076-Ag-1/ GM-Tg-bovg-IP0076-Ag-2 | Bovine FUT3 protein | Bovine |
| GM-Tg-equg-IP0076-Ag-1/ GM-Tg-equg-IP0076-Ag-2 | Equine FUT3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP0076-Ag-1/ GM-Tg-hg-IP0076-Ag-2;
GM-Tg-rg-IP0076-Ag-1/ GM-Tg-rg-IP0076-Ag-2;
GM-Tg-mg-IP0076-Ag-1/ GM-Tg-mg-IP0076-Ag-2; GM-Tg-cynog-IP0076-Ag-1/ GM-Tg-cynog-IP0076-Ag-2; GM-Tg-felg-IP0076-Ag-1/ GM-Tg-felg-IP0076-Ag-2; GM-Tg-cang-IP0076-Ag-1/ GM-Tg-cang-IP0076-Ag-2; GM-Tg-bovg-IP0076-Ag-1/ GM-Tg-bovg-IP0076-Ag-2; GM-Tg-equg-IP0076-Ag-1/ GM-Tg-equg-IP0076-Ag-2 |
| Products Name | FUT3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | FUT3 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FUT3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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Through
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strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.