Recombinant multi-species FUT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FUT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Differences in the expression of this gene are associated with host susceptibility to viral infection. [provided by RefSeq, Aug 2020]
The Alternative Names of target: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3,4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase,Alpha-3-fucosyltransferase FUT3,Blood group Lewis alpha-4-fucosyltransferase (Lewis FT),CD174,FT3B,FUT3,FucT-III,Fucosyltransferase 3,Fucosyltransferase III (FucT-III),LE,Les

Target products collectionGo to FUT3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0076-Ag-1/ GM-Tg-hg-IP0076-Ag-2 Human FUT3 protein Human
GM-Tg-rg-IP0076-Ag-1/ GM-Tg-rg-IP0076-Ag-2 Rat FUT3 protein Rat
GM-Tg-mg-IP0076-Ag-1/ GM-Tg-mg-IP0076-Ag-2 Mouse FUT3 protein Mouse
GM-Tg-cynog-IP0076-Ag-1/ GM-Tg-cynog-IP0076-Ag-2 Cynomolgus/Rhesus macaque FUT3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0076-Ag-1/ GM-Tg-felg-IP0076-Ag-2 Feline FUT3 protein Feline
GM-Tg-cang-IP0076-Ag-1/ GM-Tg-cang-IP0076-Ag-2 Canine FUT3 protein Canine
GM-Tg-bovg-IP0076-Ag-1/ GM-Tg-bovg-IP0076-Ag-2 Bovine FUT3 protein Bovine
GM-Tg-equg-IP0076-Ag-1/ GM-Tg-equg-IP0076-Ag-2 Equine FUT3 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0076-Ag-1/ GM-Tg-hg-IP0076-Ag-2; GM-Tg-rg-IP0076-Ag-1/ GM-Tg-rg-IP0076-Ag-2;
GM-Tg-mg-IP0076-Ag-1/ GM-Tg-mg-IP0076-Ag-2; GM-Tg-cynog-IP0076-Ag-1/ GM-Tg-cynog-IP0076-Ag-2;
GM-Tg-felg-IP0076-Ag-1/ GM-Tg-felg-IP0076-Ag-2; GM-Tg-cang-IP0076-Ag-1/ GM-Tg-cang-IP0076-Ag-2;
GM-Tg-bovg-IP0076-Ag-1/ GM-Tg-bovg-IP0076-Ag-2; GM-Tg-equg-IP0076-Ag-1/ GM-Tg-equg-IP0076-Ag-2
Products Name FUT3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FUT3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FUT3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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