Recombinant multi-species B7-H3/CD276 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine B7-H3/CD276 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
The Alternative Names of target: 4Ig-B7-H3,6030411F23Rik,B7 homolog 3 (B7-H3),B7-H3,B7H3,B7RP-2,B7h3,CD276,CD276 antigen,Cd276,Costimulatory molecule

Target products collectionGo to B7-H3/CD276 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0069-Ag-1/ GM-Tg-hg-IP0069-Ag-2 Human B7-H3/CD276 protein Human
GM-Tg-rg-IP0069-Ag-1/ GM-Tg-rg-IP0069-Ag-2 Rat B7-H3/CD276 protein Rat
GM-Tg-mg-IP0069-Ag-1/ GM-Tg-mg-IP0069-Ag-2 Mouse B7-H3/CD276 protein Mouse
GM-Tg-cynog-IP0069-Ag-1/ GM-Tg-cynog-IP0069-Ag-2 Cynomolgus/Rhesus macaque B7-H3/CD276 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0069-Ag-1/ GM-Tg-felg-IP0069-Ag-2 Feline B7-H3/CD276 protein Feline
GM-Tg-cang-IP0069-Ag-1/ GM-Tg-cang-IP0069-Ag-2 Canine B7-H3/CD276 protein Canine
GM-Tg-bovg-IP0069-Ag-1/ GM-Tg-bovg-IP0069-Ag-2 Bovine B7-H3/CD276 protein Bovine
GM-Tg-equg-IP0069-Ag-1/ GM-Tg-equg-IP0069-Ag-2 Equine B7-H3/CD276 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0069-Ag-1/ GM-Tg-hg-IP0069-Ag-2; GM-Tg-rg-IP0069-Ag-1/ GM-Tg-rg-IP0069-Ag-2;
GM-Tg-mg-IP0069-Ag-1/ GM-Tg-mg-IP0069-Ag-2; GM-Tg-cynog-IP0069-Ag-1/ GM-Tg-cynog-IP0069-Ag-2;
GM-Tg-felg-IP0069-Ag-1/ GM-Tg-felg-IP0069-Ag-2; GM-Tg-cang-IP0069-Ag-1/ GM-Tg-cang-IP0069-Ag-2;
GM-Tg-bovg-IP0069-Ag-1/ GM-Tg-bovg-IP0069-Ag-2; GM-Tg-equg-IP0069-Ag-1/ GM-Tg-equg-IP0069-Ag-2
Products Name B7-H3/CD276 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name B7-H3/CD276
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine B7-H3/CD276 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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