Recombinant multi-species ATR/FRP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATR/FRP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
The Alternative Names of target: ATR,Ataxia telangiectasia and Rad3-related protein,Atr,FCTCS,FRAP-related protein 1,FRP1,MEC1,SCKL,SCKL1,Serine/threonine-protein kinase ATR

Target products collectionGo to ATR/FRP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0060-Ag-1/ GM-Tg-hg-IP0060-Ag-2 Human ATR/FRP1 protein Human
GM-Tg-rg-IP0060-Ag-1/ GM-Tg-rg-IP0060-Ag-2 Rat ATR/FRP1 protein Rat
GM-Tg-mg-IP0060-Ag-1/ GM-Tg-mg-IP0060-Ag-2 Mouse ATR/FRP1 protein Mouse
GM-Tg-cynog-IP0060-Ag-1/ GM-Tg-cynog-IP0060-Ag-2 Cynomolgus/Rhesus macaque ATR/FRP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0060-Ag-1/ GM-Tg-felg-IP0060-Ag-2 Feline ATR/FRP1 protein Feline
GM-Tg-cang-IP0060-Ag-1/ GM-Tg-cang-IP0060-Ag-2 Canine ATR/FRP1 protein Canine
GM-Tg-bovg-IP0060-Ag-1/ GM-Tg-bovg-IP0060-Ag-2 Bovine ATR/FRP1 protein Bovine
GM-Tg-equg-IP0060-Ag-1/ GM-Tg-equg-IP0060-Ag-2 Equine ATR/FRP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0060-Ag-1/ GM-Tg-hg-IP0060-Ag-2; GM-Tg-rg-IP0060-Ag-1/ GM-Tg-rg-IP0060-Ag-2;
GM-Tg-mg-IP0060-Ag-1/ GM-Tg-mg-IP0060-Ag-2; GM-Tg-cynog-IP0060-Ag-1/ GM-Tg-cynog-IP0060-Ag-2;
GM-Tg-felg-IP0060-Ag-1/ GM-Tg-felg-IP0060-Ag-2; GM-Tg-cang-IP0060-Ag-1/ GM-Tg-cang-IP0060-Ag-2;
GM-Tg-bovg-IP0060-Ag-1/ GM-Tg-bovg-IP0060-Ag-2; GM-Tg-equg-IP0060-Ag-1/ GM-Tg-equg-IP0060-Ag-2
Products Name ATR/FRP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ATR/FRP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATR/FRP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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