ATR/FRP1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore ATR/FRP1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]

Target ID GM-IP0060
Target Name ATR/FRP1
Gene Group ldentifer
（Target Gene ID in Homo species) 		545
Gene ID 100062529 (Equus caballus), 100856315 (Canis lupus familiaris), 101088023 (Felis catus), 245000 (Mus musculus)
504869 (Bos taurus), 545 (Homo sapiens), 685055 (Rattus norvegicus), 714443 (Macaca mulatta)
Target Alternative Names ATR,Ataxia telangiectasia and Rad3-related protein,Atr,FCTCS,FRAP-related protein 1,FRP1,MEC1,SCKL,SCKL1,Serine/threonine-protein kinase ATR
Uniprot Accession Q9JKK8,Q13535
Protein Sub-location Introcelluar Protein
Category Therapeutics Target, Immuno-oncology Target
Disease from KEGG p53 signaling pathway, Cellular senescence, Human papillomavirus infection, Human T-cell leukemia virus 1 infection
Gene Ensembl ENSECAG00000013285, ENSCAFG00845028753, ENSMUSG00000032409, ENSBTAG00000011529, ENSG00000175054, ENSMMUG00000007927
Target Classification Kinase, Checkpoint-Immuno Oncology


Pre-made viral vector of ATR/FRP1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP-SPh-006Human ATR/FCTCS/FRP1 Lentivirus plasmidNM_001184545HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPh-146Human ATR/FCTCS/FRP1 Adenovirus plasmidNM_001184545HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMPC000882Human ATR/FCTCS/FRP1 Mammalian (Non-Viral Vector) plasmidNM_001184.4545HumanMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP-SPh-006Human ATR/FCTCS/FRP1 Lentivirus particleNM_001184545HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAP-SPh-146Human ATR/FCTCS/FRP1 Adenovirus particleNM_001184545HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail


ATR/FRP1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo545Pre-made Human ATR/FRP1/MEC1 siRNA oligo Duplex545HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo685055Pre-made Rat Atr siRNA oligo Duplex685055RatIn-vitro grade; in-vivo gradeDetail
pGMoligo245000Pre-made Mouse Atr siRNA oligo Duplex245000MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo714443Pre-made Cynomolgus/Rhesus macaque ATR siRNA oligo Duplex714443Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101088023Pre-made Cat/Feline ATR siRNA oligo Duplex101088023Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo100856315Pre-made Dog/Canine ATR siRNA oligo Duplex100856315Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo504869Pre-made Bovines/Cattle ATR siRNA oligo Duplex504869Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100062529Pre-made Equine/Horse ATR siRNA oligo Duplex100062529Equine/HorseIn-vitro grade; in-vivo gradeDetail


ATR/FRP1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-IP0060-AbHumanAnti-Human ATR/FRP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-IP0060-AbRatAnti-Rat ATR/FRP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-IP0060-AbMouseAnti-Mouse ATR/FRP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-IP0060-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque ATR/FRP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-IP0060-AbCat/FelineAnti-Cat/Feline ATR/FRP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-IP0060-AbDog/CanineAnti-Dog/Canine ATR/FRP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-IP0060-AbBovines/CattleAnti-Bovines/Cattle ATR/FRP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-IP0060-AbEquine/HorseAnti-Equine/Horse ATR/FRP1 monoclonal antibodymabTherapeutics Target antibodyDetail


ATR/FRP1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-IP0060-AgHumanHuman ATR/FRP1 recombinant proteinMammalian cellDetail
GM-Tg-rg-IP0060-AgRatRat ATR/FRP1 recombinant proteinMammalian cellDetail
GM-Tg-mg-IP0060-AgMouseMouse ATR/FRP1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-IP0060-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque ATR/FRP1 recombinant proteinMammalian cellDetail
GM-Tg-felg-IP0060-AgCat/FelineCat/Feline ATR/FRP1 recombinant proteinMammalian cellDetail
GM-Tg-cang-IP0060-AgDog/CanineDog/Canine ATR/FRP1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-IP0060-AgBovines/CattleBovines/Cattle ATR/FRP1 recombinant proteinMammalian cellDetail
GM-Tg-equg-IP0060-AgEquine/HorseEquine/Horse ATR/FRP1 recombinant proteinMammalian cellDetail