Recombinant multi-species MAPKAPK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAPKAPK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: MAP kinase-activated protein kinase 2,MAPK-activated protein kinase 2,MAPKAP kinase 2,MAPKAP-K2,MAPKAPK-2,MAPKAPK2,MK-2,MK2,Mapkapk2,Rps6kc1

Target products collectionGo to MAPKAPK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0057-Ag-1/ GM-Tg-hg-IP0057-Ag-2 Human MAPKAPK2 protein Human
GM-Tg-rg-IP0057-Ag-1/ GM-Tg-rg-IP0057-Ag-2 Rat MAPKAPK2 protein Rat
GM-Tg-mg-IP0057-Ag-1/ GM-Tg-mg-IP0057-Ag-2 Mouse MAPKAPK2 protein Mouse
GM-Tg-cynog-IP0057-Ag-1/ GM-Tg-cynog-IP0057-Ag-2 Cynomolgus/Rhesus macaque MAPKAPK2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0057-Ag-1/ GM-Tg-felg-IP0057-Ag-2 Feline MAPKAPK2 protein Feline
GM-Tg-cang-IP0057-Ag-1/ GM-Tg-cang-IP0057-Ag-2 Canine MAPKAPK2 protein Canine
GM-Tg-bovg-IP0057-Ag-1/ GM-Tg-bovg-IP0057-Ag-2 Bovine MAPKAPK2 protein Bovine
GM-Tg-equg-IP0057-Ag-1/ GM-Tg-equg-IP0057-Ag-2 Equine MAPKAPK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0057-Ag-1/ GM-Tg-hg-IP0057-Ag-2; GM-Tg-rg-IP0057-Ag-1/ GM-Tg-rg-IP0057-Ag-2;
GM-Tg-mg-IP0057-Ag-1/ GM-Tg-mg-IP0057-Ag-2; GM-Tg-cynog-IP0057-Ag-1/ GM-Tg-cynog-IP0057-Ag-2;
GM-Tg-felg-IP0057-Ag-1/ GM-Tg-felg-IP0057-Ag-2; GM-Tg-cang-IP0057-Ag-1/ GM-Tg-cang-IP0057-Ag-2;
GM-Tg-bovg-IP0057-Ag-1/ GM-Tg-bovg-IP0057-Ag-2; GM-Tg-equg-IP0057-Ag-1/ GM-Tg-equg-IP0057-Ag-2
Products Name MAPKAPK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MAPKAPK2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAPKAPK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.