Explore MAPKAPK2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0057
|
| Target Name |
MAPKAPK2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9261
|
| Gene ID |
100055510 (Equus caballus), 101090833 (Felis catus), 17164 (Mus musculus), 289014 (Rattus norvegicus)
490263 (Canis lupus familiaris), 695044 (Macaca mulatta), 788091 (Bos taurus), 9261 (Homo sapiens)
|
| Target Alternative Names |
MAP kinase-activated protein kinase 2,MAPK-activated protein kinase 2,MAPKAP kinase 2,MAPKAP-K2,MAPKAPK-2,MAPKAPK2,MK-2,MK2,Mapkapk2,Rps6kc1
|
| Uniprot Accession |
P49138,P49137
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
MAPK signaling pathway, Cellular senescence, C-type lectin receptor signaling pathway, Neurotrophin signaling pathway, Kaposi sarcoma-associated herpesvirus infection
|
| Gene Ensembl |
ENSECAG00000021899, ENSMUSG00000016528, ENSMMUG00000023567, ENSBTAG00000038107, ENSG00000162889
|
| Target Classification |
Kinase
|
Pre-made viral vector of MAPKAPK2 cDNA Clones/ORF Plasmid
MAPKAPK2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9261 | Pre-made Human MAPKAPK2/MK2/MK-2 siRNA oligo Duplex | 9261 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo289014 | Pre-made Rat Mapkapk2 siRNA oligo Duplex | 289014 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17164 | Pre-made Mouse Mapkapk2/MK2/MK-2 siRNA oligo Duplex | 17164 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695044 | Pre-made Cynomolgus/Rhesus macaque MAPKAPK2 siRNA oligo Duplex | 695044 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090833 | Pre-made Cat/Feline MAPKAPK2 siRNA oligo Duplex | 101090833 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490263 | Pre-made Dog/Canine MAPKAPK2 siRNA oligo Duplex | 490263 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo788091 | Pre-made Bovines/Cattle MAPKAPK2 siRNA oligo Duplex | 788091 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055510 | Pre-made Equine/Horse MAPKAPK2 siRNA oligo Duplex | 100055510 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MAPKAPK2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0057-Ab | Human | Anti-Human MAPKAPK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0057-Ab | Rat | Anti-Rat MAPKAPK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0057-Ab | Mouse | Anti-Mouse MAPKAPK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0057-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAPKAPK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0057-Ab | Cat/Feline | Anti-Cat/Feline MAPKAPK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0057-Ab | Dog/Canine | Anti-Dog/Canine MAPKAPK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0057-Ab | Bovines/Cattle | Anti-Bovines/Cattle MAPKAPK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0057-Ab | Equine/Horse | Anti-Equine/Horse MAPKAPK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MAPKAPK2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0057-Ag | Human | Human MAPKAPK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0057-Ag | Rat | Rat MAPKAPK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0057-Ag | Mouse | Mouse MAPKAPK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0057-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAPKAPK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0057-Ag | Cat/Feline | Cat/Feline MAPKAPK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0057-Ag | Dog/Canine | Dog/Canine MAPKAPK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0057-Ag | Bovines/Cattle | Bovines/Cattle MAPKAPK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0057-Ag | Equine/Horse | Equine/Horse MAPKAPK2 recombinant protein | Mammalian cell | Detail |
