Recombinant multi-species HO-1/HMOX1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HO-1/HMOX1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]
The Alternative Names of target: D8Wsu38e,HEOXG,HMOX1,HMOX1D,HO-1,HO1,HSP32,Heme oxygenase 1,Hemox,Heox,Hmox,Hmox1,Ho-1,Ho1,Hsp32,bK286B10,hsp32

Target products collectionGo to HO-1/HMOX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0044-Ag-1/ GM-Tg-hg-IP0044-Ag-2 Human HO-1/HMOX1 protein Human
GM-Tg-rg-IP0044-Ag-1/ GM-Tg-rg-IP0044-Ag-2 Rat HO-1/HMOX1 protein Rat
GM-Tg-mg-IP0044-Ag-1/ GM-Tg-mg-IP0044-Ag-2 Mouse HO-1/HMOX1 protein Mouse
GM-Tg-cynog-IP0044-Ag-1/ GM-Tg-cynog-IP0044-Ag-2 Cynomolgus/Rhesus macaque HO-1/HMOX1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0044-Ag-1/ GM-Tg-felg-IP0044-Ag-2 Feline HO-1/HMOX1 protein Feline
GM-Tg-cang-IP0044-Ag-1/ GM-Tg-cang-IP0044-Ag-2 Canine HO-1/HMOX1 protein Canine
GM-Tg-bovg-IP0044-Ag-1/ GM-Tg-bovg-IP0044-Ag-2 Bovine HO-1/HMOX1 protein Bovine
GM-Tg-equg-IP0044-Ag-1/ GM-Tg-equg-IP0044-Ag-2 Equine HO-1/HMOX1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0044-Ag-1/ GM-Tg-hg-IP0044-Ag-2; GM-Tg-rg-IP0044-Ag-1/ GM-Tg-rg-IP0044-Ag-2;
GM-Tg-mg-IP0044-Ag-1/ GM-Tg-mg-IP0044-Ag-2; GM-Tg-cynog-IP0044-Ag-1/ GM-Tg-cynog-IP0044-Ag-2;
GM-Tg-felg-IP0044-Ag-1/ GM-Tg-felg-IP0044-Ag-2; GM-Tg-cang-IP0044-Ag-1/ GM-Tg-cang-IP0044-Ag-2;
GM-Tg-bovg-IP0044-Ag-1/ GM-Tg-bovg-IP0044-Ag-2; GM-Tg-equg-IP0044-Ag-1/ GM-Tg-equg-IP0044-Ag-2
Products Name HO-1/HMOX1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HO-1/HMOX1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HO-1/HMOX1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.