Recombinant multi-species FANCA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FANCA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008]
The Alternative Names of target: FA,FA-H,FA1,FAA,FACA,FAH,FANCA,FANCH,Fanca,Fanconi anemia group A protein,Protein FACA,ZNF276

Target products collectionGo to FANCA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0029-Ag-1/ GM-Tg-hg-IP0029-Ag-2 Human FANCA protein Human
GM-Tg-rg-IP0029-Ag-1/ GM-Tg-rg-IP0029-Ag-2 Rat FANCA protein Rat
GM-Tg-mg-IP0029-Ag-1/ GM-Tg-mg-IP0029-Ag-2 Mouse FANCA protein Mouse
GM-Tg-cynog-IP0029-Ag-1/ GM-Tg-cynog-IP0029-Ag-2 Cynomolgus/Rhesus macaque FANCA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0029-Ag-1/ GM-Tg-felg-IP0029-Ag-2 Feline FANCA protein Feline
GM-Tg-cang-IP0029-Ag-1/ GM-Tg-cang-IP0029-Ag-2 Canine FANCA protein Canine
GM-Tg-bovg-IP0029-Ag-1/ GM-Tg-bovg-IP0029-Ag-2 Bovine FANCA protein Bovine
GM-Tg-equg-IP0029-Ag-1/ GM-Tg-equg-IP0029-Ag-2 Equine FANCA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0029-Ag-1/ GM-Tg-hg-IP0029-Ag-2; GM-Tg-rg-IP0029-Ag-1/ GM-Tg-rg-IP0029-Ag-2;
GM-Tg-mg-IP0029-Ag-1/ GM-Tg-mg-IP0029-Ag-2; GM-Tg-cynog-IP0029-Ag-1/ GM-Tg-cynog-IP0029-Ag-2;
GM-Tg-felg-IP0029-Ag-1/ GM-Tg-felg-IP0029-Ag-2; GM-Tg-cang-IP0029-Ag-1/ GM-Tg-cang-IP0029-Ag-2;
GM-Tg-bovg-IP0029-Ag-1/ GM-Tg-bovg-IP0029-Ag-2; GM-Tg-equg-IP0029-Ag-1/ GM-Tg-equg-IP0029-Ag-2
Products Name FANCA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FANCA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FANCA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.