Recombinant multi-species EIF2AK3/PERK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF2AK3/PERK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
The Alternative Names of target: EIF2AK3,Eif2ak3,Eukaryotic translation initiation factor 2-alpha kinase 3,PEK,PERK,PRKR-like endoplasmic reticulum kinase,Pancreatic eIF2-alpha kinase (HsPEK),Pek,Perk,Protein tyrosine kinase EIF2AK3,WRS

Target products collectionGo to EIF2AK3/PERK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0003-Ag-1/ GM-Tg-hg-IP0003-Ag-2 Human EIF2AK3/PERK protein Human
GM-Tg-rg-IP0003-Ag-1/ GM-Tg-rg-IP0003-Ag-2 Rat EIF2AK3/PERK protein Rat
GM-Tg-mg-IP0003-Ag-1/ GM-Tg-mg-IP0003-Ag-2 Mouse EIF2AK3/PERK protein Mouse
GM-Tg-cynog-IP0003-Ag-1/ GM-Tg-cynog-IP0003-Ag-2 Cynomolgus/Rhesus macaque EIF2AK3/PERK protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0003-Ag-1/ GM-Tg-felg-IP0003-Ag-2 Feline EIF2AK3/PERK protein Feline
GM-Tg-cang-IP0003-Ag-1/ GM-Tg-cang-IP0003-Ag-2 Canine EIF2AK3/PERK protein Canine
GM-Tg-bovg-IP0003-Ag-1/ GM-Tg-bovg-IP0003-Ag-2 Bovine EIF2AK3/PERK protein Bovine
GM-Tg-equg-IP0003-Ag-1/ GM-Tg-equg-IP0003-Ag-2 Equine EIF2AK3/PERK protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0003-Ag-1/ GM-Tg-hg-IP0003-Ag-2; GM-Tg-rg-IP0003-Ag-1/ GM-Tg-rg-IP0003-Ag-2;
GM-Tg-mg-IP0003-Ag-1/ GM-Tg-mg-IP0003-Ag-2; GM-Tg-cynog-IP0003-Ag-1/ GM-Tg-cynog-IP0003-Ag-2;
GM-Tg-felg-IP0003-Ag-1/ GM-Tg-felg-IP0003-Ag-2; GM-Tg-cang-IP0003-Ag-1/ GM-Tg-cang-IP0003-Ag-2;
GM-Tg-bovg-IP0003-Ag-1/ GM-Tg-bovg-IP0003-Ag-2; GM-Tg-equg-IP0003-Ag-1/ GM-Tg-equg-IP0003-Ag-2
Products Name EIF2AK3/PERK protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name EIF2AK3/PERK
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EIF2AK3/PERK protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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