Recombinant multi-species RORC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RORC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: IMD42,NR1F3,Nr1f3,Nuclear receptor ROR-gamma,Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,RORC,RORG,RORgamma,RZR-GAMMA,RZRG,Retinoid-related orphan receptor-gamma,Rorc,TOR,Thor

Target products collectionGo to RORC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IO129-Ag-1/ GM-Tg-hg-IO129-Ag-2 Human RORC protein Human
GM-Tg-rg-IO129-Ag-1/ GM-Tg-rg-IO129-Ag-2 Rat RORC protein Rat
GM-Tg-mg-IO129-Ag-1/ GM-Tg-mg-IO129-Ag-2 Mouse RORC protein Mouse
GM-Tg-cynog-IO129-Ag-1/ GM-Tg-cynog-IO129-Ag-2 Cynomolgus/Rhesus macaque RORC protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IO129-Ag-1/ GM-Tg-felg-IO129-Ag-2 Feline RORC protein Feline
GM-Tg-cang-IO129-Ag-1/ GM-Tg-cang-IO129-Ag-2 Canine RORC protein Canine
GM-Tg-bovg-IO129-Ag-1/ GM-Tg-bovg-IO129-Ag-2 Bovine RORC protein Bovine
GM-Tg-equg-IO129-Ag-1/ GM-Tg-equg-IO129-Ag-2 Equine RORC protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IO129-Ag-1/ GM-Tg-hg-IO129-Ag-2; GM-Tg-rg-IO129-Ag-1/ GM-Tg-rg-IO129-Ag-2;
GM-Tg-mg-IO129-Ag-1/ GM-Tg-mg-IO129-Ag-2; GM-Tg-cynog-IO129-Ag-1/ GM-Tg-cynog-IO129-Ag-2;
GM-Tg-felg-IO129-Ag-1/ GM-Tg-felg-IO129-Ag-2; GM-Tg-cang-IO129-Ag-1/ GM-Tg-cang-IO129-Ag-2;
GM-Tg-bovg-IO129-Ag-1/ GM-Tg-bovg-IO129-Ag-2; GM-Tg-equg-IO129-Ag-1/ GM-Tg-equg-IO129-Ag-2
Products Name RORC protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RORC
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RORC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.