Anti-KU70/XRCC6 monoclonal antibody
The Alternative Names of target: 5'-deoxyribose-5-phosphate lyase Ku70 (5'-dRP lyase Ku70),70 kDa subunit of Ku antigen,70kDa,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit (CTC75,CTC75,CTCBF,CTCBF),DNA repair protein XRCC6,G22P1,G22p1,KU70,Ku70,Kup70,Lupus Ku autoantigen protein p70 (Ku70),ML8,TLAA,Thyroid-lupus autoantigen (TLAA),X-ray repair complementing defective repair in Chinese hamster cells 6,X-ray repair cross-complementing protein 6,XRCC6,Xrcc6
Pre-made anti-KU70/XRCC6 monoclonal antibody (mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0563-Ab-1/ GM-Tg-hg-SE0563-Ab-2 | Anti-Human KU70/XRCC6 monoclonal antibody | Human |
| GM-Tg-rg-SE0563-Ab-1/ GM-Tg-rg-SE0563-Ab-2 | Anti-Rat KU70/XRCC6 monoclonal antibody | Rat |
| GM-Tg-mg-SE0563-Ab-1/ GM-Tg-mg-SE0563-Ab-2 | Anti-Mouse KU70/XRCC6 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0563-Ab-1/ GM-Tg-cynog-SE0563-Ab-2 | Anti-Cynomolgus/Rhesus macaque KU70/XRCC6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0563-Ab-1/ GM-Tg-felg-SE0563-Ab-2 | Anti-Feline KU70/XRCC6 monoclonal antibody | Feline |
| GM-Tg-cang-SE0563-Ab-1/ GM-Tg-cang-SE0563-Ab-2 | Anti-Canine KU70/XRCC6 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0563-Ab-1/ GM-Tg-bovg-SE0563-Ab-2 | Anti-Bovine KU70/XRCC6 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0563-Ab-1/ GM-Tg-equg-SE0563-Ab-2 | Anti-Equine KU70/XRCC6 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0563-Ab-1/ GM-Tg-hg-SE0563-Ab-2;
GM-Tg-rg-SE0563-Ab-1/ GM-Tg-rg-SE0563-Ab-2;
GM-Tg-mg-SE0563-Ab-1/ GM-Tg-mg-SE0563-Ab-2; GM-Tg-cynog-SE0563-Ab-1/ GM-Tg-cynog-SE0563-Ab-2; GM-Tg-felg-SE0563-Ab-1/ GM-Tg-felg-SE0563-Ab-2; GM-Tg-cang-SE0563-Ab-1/ GM-Tg-cang-SE0563-Ab-2; GM-Tg-bovg-SE0563-Ab-1/ GM-Tg-bovg-SE0563-Ab-2; GM-Tg-equg-SE0563-Ab-1/ GM-Tg-equg-SE0563-Ab-2 |
| Products Name | Anti-KU70/XRCC6 monoclonal antibody |
| Format | mab |
| Target Name | KU70/XRCC6 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) |
IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-KU70/XRCC6 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.