Explore POLG gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-TA183
|
| Target Name |
POLG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5428
|
| Gene ID |
100053827 (Equus caballus), 100856383 (Canis lupus familiaris), 101083771 (Felis catus), 18975 (Mus musculus)
533090 (Bos taurus), 5428 (Homo sapiens), 699750 (Macaca mulatta), 85472 (Rattus norvegicus)
|
| Target Alternative Names |
POLG,Polg,PolgA,PEO,MDP1,SCAE,MIRAS,POLG1,POLGA,SANDO,MTDPS4A,MTDPS4B
|
| Uniprot Accession |
P54099,P54098,Q9QYV8
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000007781, ENSCAFG00845004161, ENSMUSG00000039176, ENSBTAG00000009098, ENSG00000140521, ENSMMUG00000011160
|
| Target Classification |
|
POLG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5428 | Pre-made Human POLG/PEO/MDP1 siRNA oligo Duplex | 5428 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo85472 | Pre-made Rat Polg siRNA oligo Duplex | 85472 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18975 | Pre-made Mouse Polg/PolgA siRNA oligo Duplex | 18975 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699750 | Pre-made Cynomolgus/Rhesus macaque POLG siRNA oligo Duplex | 699750 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083771 | Pre-made Cat/Feline POLG siRNA oligo Duplex | 101083771 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856383 | Pre-made Dog/Canine POLG siRNA oligo Duplex | 100856383 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533090 | Pre-made Bovines/Cattle POLG siRNA oligo Duplex | 533090 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053827 | Pre-made Equine/Horse POLG siRNA oligo Duplex | 100053827 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
POLG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA183-Ab | Human | Anti-Human POLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA183-Ab | Rat | Anti-Rat POLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA183-Ab | Mouse | Anti-Mouse POLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA183-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque POLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA183-Ab | Cat/Feline | Anti-Cat/Feline POLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA183-Ab | Dog/Canine | Anti-Dog/Canine POLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA183-Ab | Bovines/Cattle | Anti-Bovines/Cattle POLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA183-Ab | Equine/Horse | Anti-Equine/Horse POLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
POLG recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA183-Ag | Human | Human POLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA183-Ag | Rat | Rat POLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA183-Ag | Mouse | Mouse POLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA183-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque POLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA183-Ag | Cat/Feline | Cat/Feline POLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA183-Ag | Dog/Canine | Dog/Canine POLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA183-Ag | Bovines/Cattle | Bovines/Cattle POLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA183-Ag | Equine/Horse | Equine/Horse POLG recombinant protein | Mammalian cell | Detail |
