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Target
sublocation: Introcelluar Protein.
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]
| Target ID |
GM-TA096
|
| Target Name |
FNTA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2339
|
| Gene ID |
100053704 (Equus caballus), 101097062 (Felis catus), 14272 (Mus musculus), 2339 (Homo sapiens)
25318 (Rattus norvegicus), 281169 (Bos taurus), 475566 (Canis lupus familiaris), 712681 (Macaca mulatta)
|
| Target Alternative Names |
CAAX farnesyltransferase subunit alpha,FNTA,FPTA,FTA,FTase-alpha,Fnta,PFAS,PGGT1A,PTAR2,Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha,Ras proteins prenyltransferase subunit alpha,Type I protein geranyl-geranyltransferase subunit alpha (GGTase-I-alpha)
|
| Uniprot Accession |
Q61239,P49354,Q04631,P29702
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSMUSG00000015994, ENSG00000168522, ENSBTAG00000003201, ENSCAFG00845017026, ENSMMUG00000019866
|
| Target Classification |
|
Pre-made viral vector of FNTA cDNA Clones/ORF Plasmid
FNTA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2339 | Pre-made Human FNTA/FPTA/PTAR2 siRNA oligo Duplex | 2339 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25318 | Pre-made Rat Fnta/PFAS siRNA oligo Duplex | 25318 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14272 | Pre-made Mouse Fnta/FTA siRNA oligo Duplex | 14272 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712681 | Pre-made Cynomolgus/Rhesus macaque FNTA siRNA oligo Duplex | 712681 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097062 | Pre-made Cat/Feline FNTA siRNA oligo Duplex | 101097062 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475566 | Pre-made Dog/Canine FNTA siRNA oligo Duplex | 475566 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281169 | Pre-made Bovines/Cattle FNTA siRNA oligo Duplex | 281169 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053704 | Pre-made Equine/Horse FNTA siRNA oligo Duplex | 100053704 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FNTA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA096-Ab | Human | Anti-Human FNTA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA096-Ab | Rat | Anti-Rat FNTA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA096-Ab | Mouse | Anti-Mouse FNTA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA096-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FNTA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA096-Ab | Cat/Feline | Anti-Cat/Feline FNTA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA096-Ab | Dog/Canine | Anti-Dog/Canine FNTA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA096-Ab | Bovines/Cattle | Anti-Bovines/Cattle FNTA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA096-Ab | Equine/Horse | Anti-Equine/Horse FNTA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
FNTA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA096-Ag | Human | Human FNTA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA096-Ag | Rat | Rat FNTA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA096-Ag | Mouse | Mouse FNTA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA096-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FNTA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA096-Ag | Cat/Feline | Cat/Feline FNTA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA096-Ag | Dog/Canine | Dog/Canine FNTA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA096-Ag | Bovines/Cattle | Bovines/Cattle FNTA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA096-Ag | Equine/Horse | Equine/Horse FNTA recombinant protein | Mammalian cell | Detail |
