Recombinant multi-species FNTA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FNTA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]
The Alternative Names of target: CAAX farnesyltransferase subunit alpha,FNTA,FPTA,FTA,FTase-alpha,Fnta,PFAS,PGGT1A,PTAR2,Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha,Ras proteins prenyltransferase subunit alpha,Type I protein geranyl-geranyltransferase subunit alpha (GGTase-I-alpha)

Target products collectionGo to FNTA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA096-Ag-1/ GM-Tg-hg-TA096-Ag-2 Human FNTA protein Human
GM-Tg-rg-TA096-Ag-1/ GM-Tg-rg-TA096-Ag-2 Rat FNTA protein Rat
GM-Tg-mg-TA096-Ag-1/ GM-Tg-mg-TA096-Ag-2 Mouse FNTA protein Mouse
GM-Tg-cynog-TA096-Ag-1/ GM-Tg-cynog-TA096-Ag-2 Cynomolgus/Rhesus macaque FNTA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA096-Ag-1/ GM-Tg-felg-TA096-Ag-2 Feline FNTA protein Feline
GM-Tg-cang-TA096-Ag-1/ GM-Tg-cang-TA096-Ag-2 Canine FNTA protein Canine
GM-Tg-bovg-TA096-Ag-1/ GM-Tg-bovg-TA096-Ag-2 Bovine FNTA protein Bovine
GM-Tg-equg-TA096-Ag-1/ GM-Tg-equg-TA096-Ag-2 Equine FNTA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA096-Ag-1/ GM-Tg-hg-TA096-Ag-2; GM-Tg-rg-TA096-Ag-1/ GM-Tg-rg-TA096-Ag-2;
GM-Tg-mg-TA096-Ag-1/ GM-Tg-mg-TA096-Ag-2; GM-Tg-cynog-TA096-Ag-1/ GM-Tg-cynog-TA096-Ag-2;
GM-Tg-felg-TA096-Ag-1/ GM-Tg-felg-TA096-Ag-2; GM-Tg-cang-TA096-Ag-1/ GM-Tg-cang-TA096-Ag-2;
GM-Tg-bovg-TA096-Ag-1/ GM-Tg-bovg-TA096-Ag-2; GM-Tg-equg-TA096-Ag-1/ GM-Tg-equg-TA096-Ag-2
Products Name FNTA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FNTA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FNTA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.