CD8/CD8A/CD8a Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore CD8/CD8A/CD8a gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]

Target ID GM-TA040
Target Name CD8/CD8A/CD8a
Gene Group ldentifer
(Target Gene ID in Homo species)
925
Gene ID 100066774 (Equus caballus), 12525 (Mus musculus), 24930 (Rattus norvegicus), 281060 (Bos taurus)
403157 (Canis lupus familiaris), 493799 (Felis catus), 698329 (Macaca mulatta), 925 (Homo sapiens)
Target Alternative Names CD8,CD8A,CD8a,CD8alpha,Cd8a,IMD116,Leu2,Ly-2,Ly-35,Ly-B,Lyt-2,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2,p32
Uniprot Accession P01731,P07725,P31783,P33706,P41688,P01732
Protein Sub-location Transmembrane Protein
Category Therapeutics Target, Immuno-oncology Target
Disease from KEGG Cell adhesion molecules, Antigen processing and presentation, Hematopoietic cell lineage, T cell receptor signaling pathway, Yersinia infection
Gene Ensembl ENSECAG00000013261, ENSMUSG00000053977, ENSBTAG00000021141, ENSCAFG00845013158, ENSMMUG00000003524, ENSG00000153563
Target Classification Checkpoint-Immuno Oncology


Pre-made viral vector of CD8/CD8A/CD8a cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP004474Human CD8A/CD8/Leu2 Lentivirus plasmidNM_001768925HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP004474Human CD8A/CD8/Leu2 Lentivirus particleNM_001768925HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm000479Mouse Cd8a/BB154331/Ly-2 Lentivirus plasmidNM_00108111012525MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm000479Mouse Cd8a/BB154331/Ly-2 Lentivirus particleNM_00108111012525MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


CD8/CD8A/CD8a siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo925Pre-made Human CD8A/CD8/p32 siRNA oligo Duplex925HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo24930Pre-made Rat Cd8a siRNA oligo Duplex24930RatIn-vitro grade; in-vivo gradeDetail
pGMoligo12525Pre-made Mouse Cd8a/Ly-2/Ly-B siRNA oligo Duplex12525MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo698329Pre-made Cynomolgus/Rhesus macaque CD8A siRNA oligo Duplex698329Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo493799Pre-made Cat/Feline CD8A siRNA oligo Duplex493799Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403157Pre-made Dog/Canine CD8A siRNA oligo Duplex403157Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo281060Pre-made Bovines/Cattle CD8A siRNA oligo Duplex281060Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100066774Pre-made Equine/Horse CD8A siRNA oligo Duplex100066774Equine/HorseIn-vitro grade; in-vivo gradeDetail


CD8/CD8A/CD8a antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-TA040-AbHumanAnti-Human CD8/CD8A/CD8a monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-TA040-AbRatAnti-Rat CD8/CD8A/CD8a monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-TA040-AbMouseAnti-Mouse CD8/CD8A/CD8a monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-TA040-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque CD8/CD8A/CD8a monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-TA040-AbCat/FelineAnti-Cat/Feline CD8/CD8A/CD8a monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-TA040-AbDog/CanineAnti-Dog/Canine CD8/CD8A/CD8a monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-TA040-AbBovines/CattleAnti-Bovines/Cattle CD8/CD8A/CD8a monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-TA040-AbEquine/HorseAnti-Equine/Horse CD8/CD8A/CD8a monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


CD8/CD8A/CD8a VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-TA040-AgHumanHuman CD8/CD8A/CD8a VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-TA040-AgRatRat CD8/CD8A/CD8a VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-TA040-AgMouseMouse CD8/CD8A/CD8a VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-TA040-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque CD8/CD8A/CD8a VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-TA040-AgCat/FelineCat/Feline CD8/CD8A/CD8a VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-TA040-AgDog/CanineDog/Canine CD8/CD8A/CD8a VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-TA040-AgBovines/CattleBovines/Cattle CD8/CD8A/CD8a VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-TA040-AgEquine/HorseEquine/Horse CD8/CD8A/CD8a VLP (virus-like particle)HEK293Products Developing