Explore DPM1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
| Target ID |
GM-TA006
|
| Target Name |
DPM1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8813
|
| Gene ID |
100052367 (Equus caballus), 101098859 (Felis catus), 13480 (Mus musculus), 296394 (Rattus norvegicus)
477264 (Canis lupus familiaris), 534097 (Bos taurus), 701283 (Macaca mulatta), 8813 (Homo sapiens)
|
| Target Alternative Names |
CDGIE,DPM1,DPMS,Dolichol-phosphate mannose synthase subunit 1 (DPM synthase subunit 1),Dolichol-phosphate mannosyltransferase subunit 1,Dolichyl-phosphate beta-D-mannosyltransferase subunit 1,Dpm1,MPDS,Mannose-P-dolichol synthase subunit 1 (MPD synthase subunit 1)
|
| Uniprot Accession |
O70152,Q1JQ93,O60762
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways, N-Glycan biosynthesis
|
| Gene Ensembl |
ENSECAG00000011277, ENSMUSG00000078919, ENSCAFG00845026765, ENSBTAG00000007721, ENSMMUG00000002759, ENSG00000000419
|
| Target Classification |
|
DPM1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8813 | Pre-made Human DPM1/MPDS/CDGIE siRNA oligo Duplex | 8813 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo296394 | Pre-made Rat Dpm1 siRNA oligo Duplex | 296394 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13480 | Pre-made Mouse Dpm1 siRNA oligo Duplex | 13480 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701283 | Pre-made Cynomolgus/Rhesus macaque DPM1 siRNA oligo Duplex | 701283 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098859 | Pre-made Cat/Feline DPM1 siRNA oligo Duplex | 101098859 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477264 | Pre-made Dog/Canine DPM1 siRNA oligo Duplex | 477264 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534097 | Pre-made Bovines/Cattle DPM1/DPMS siRNA oligo Duplex | 534097 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052367 | Pre-made Equine/Horse DPM1 siRNA oligo Duplex | 100052367 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DPM1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA006-Ab | Human | Anti-Human DPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA006-Ab | Rat | Anti-Rat DPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA006-Ab | Mouse | Anti-Mouse DPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA006-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA006-Ab | Cat/Feline | Anti-Cat/Feline DPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA006-Ab | Dog/Canine | Anti-Dog/Canine DPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA006-Ab | Bovines/Cattle | Anti-Bovines/Cattle DPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA006-Ab | Equine/Horse | Anti-Equine/Horse DPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
DPM1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA006-Ag | Human | Human DPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA006-Ag | Rat | Rat DPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA006-Ag | Mouse | Mouse DPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA006-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA006-Ag | Cat/Feline | Cat/Feline DPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA006-Ag | Dog/Canine | Dog/Canine DPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA006-Ag | Bovines/Cattle | Bovines/Cattle DPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA006-Ag | Equine/Horse | Equine/Horse DPM1 recombinant protein | Mammalian cell | Detail |
