Recombinant multi-species DPM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DPM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
The Alternative Names of target: CDGIE,DPM1,DPMS,Dolichol-phosphate mannose synthase subunit 1 (DPM synthase subunit 1),Dolichol-phosphate mannosyltransferase subunit 1,Dolichyl-phosphate beta-D-mannosyltransferase subunit 1,Dpm1,MPDS,Mannose-P-dolichol synthase subunit 1 (MPD synthase subunit 1)

Target products collectionGo to DPM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA006-Ag-1/ GM-Tg-hg-TA006-Ag-2 Human DPM1 protein Human
GM-Tg-rg-TA006-Ag-1/ GM-Tg-rg-TA006-Ag-2 Rat DPM1 protein Rat
GM-Tg-mg-TA006-Ag-1/ GM-Tg-mg-TA006-Ag-2 Mouse DPM1 protein Mouse
GM-Tg-cynog-TA006-Ag-1/ GM-Tg-cynog-TA006-Ag-2 Cynomolgus/Rhesus macaque DPM1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA006-Ag-1/ GM-Tg-felg-TA006-Ag-2 Feline DPM1 protein Feline
GM-Tg-cang-TA006-Ag-1/ GM-Tg-cang-TA006-Ag-2 Canine DPM1 protein Canine
GM-Tg-bovg-TA006-Ag-1/ GM-Tg-bovg-TA006-Ag-2 Bovine DPM1 protein Bovine
GM-Tg-equg-TA006-Ag-1/ GM-Tg-equg-TA006-Ag-2 Equine DPM1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA006-Ag-1/ GM-Tg-hg-TA006-Ag-2; GM-Tg-rg-TA006-Ag-1/ GM-Tg-rg-TA006-Ag-2;
GM-Tg-mg-TA006-Ag-1/ GM-Tg-mg-TA006-Ag-2; GM-Tg-cynog-TA006-Ag-1/ GM-Tg-cynog-TA006-Ag-2;
GM-Tg-felg-TA006-Ag-1/ GM-Tg-felg-TA006-Ag-2; GM-Tg-cang-TA006-Ag-1/ GM-Tg-cang-TA006-Ag-2;
GM-Tg-bovg-TA006-Ag-1/ GM-Tg-bovg-TA006-Ag-2; GM-Tg-equg-TA006-Ag-1/ GM-Tg-equg-TA006-Ag-2
Products Name DPM1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DPM1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DPM1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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