BRAF Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore BRAF gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]

Target ID GM-T99089
Target Name BRAF
Gene Group ldentifer
（Target Gene ID in Homo species) 		673
Gene ID 100065760 (Equus caballus), 101092346 (Felis catus), 109880 (Mus musculus), 114486 (Rattus norvegicus)
475526 (Canis lupus familiaris), 536051 (Bos taurus), 673 (Homo sapiens), 693554 (Macaca mulatta)
Target Alternative Names 9930012E13Rik,B-RAF1,B-raf,BRAF,BRAF-1,BRAF1,Braf,Braf-2,Braf2,C230098H17,D6Ertd631e,NS7,Proto-oncogene B-Raf,RAFB1,Serine/threonine-protein kinase B-raf,p94,v-Raf murine sarcoma viral oncogene homolog B1
Uniprot Accession P28028,P15056
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer, Non-Small Cell Lung Cancer, Colorectal Cancer, Melanoma Cancer
Disease from KEGG EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, FoxO signaling pathway, Vascular smooth muscle contraction, Focal adhesion, Natural killer cell mediated cytotoxicity, Long-term potentiation, Neurotrophin signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Alzheimer disease, Hepatitis C, Hepatitis B, Pathways in cancer, Proteoglycans in cancer, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer
Gene Ensembl ENSECAG00000002746, ENSMUSG00000002413, ENSCAFG00845031038, ENSBTAG00000021761, ENSG00000157764, ENSMMUG00000042793
Target Classification Kinase


Pre-made viral vector of BRAF cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001460Human BRAF/B-raf/B-RAF1 Lentivirus plasmidNM_004333673HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP005611Human BRAF/B-raf/B-RAF1 Lentivirus plasmidNM_004333.4673HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV000626Human BRAF/B-raf/B-RAF1 Lentivirus plasmidNM_004333.5673HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV000876Human BRAF/B-raf/B-RAF1 Lentivirus plasmidNM_004333673HumanLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMPC000733Human BRAF/B-raf/B-RAF1 Mammalian (Non-Viral Vector) plasmidNM_004333.6673HumanMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP001460Human BRAF/B-raf/B-RAF1 Lentivirus particleNM_004333673HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005611Human BRAF/B-raf/B-RAF1 Lentivirus particleNM_004333.4673HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000626Human BRAF/B-raf/B-RAF1 Lentivirus particleNM_004333.5673HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000876Human BRAF/B-raf/B-RAF1 Lentivirus particleNM_004333673HumanLentivirus particleNull3xflag (C-Terminal)CMVDetail
pGMAD000879Mouse Braf/9930012E13Rik/AA120551 Adenovirus plasmidNM_139294.5109880MouseAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
vGMAD000879Mouse Braf/9930012E13Rik/AA120551 Adenovirus particleNM_139294.5109880MouseAdenovirus particleNull3xflag (C-Terminal)CMVDetail


BRAF siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo673Pre-made Human BRAF/NS7/B-raf siRNA oligo Duplex673HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo114486Pre-made Rat Braf siRNA oligo Duplex114486RatIn-vitro grade; in-vivo gradeDetail
pGMoligo109880Pre-made Mouse Braf/B-raf/Braf2 siRNA oligo Duplex109880MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo693554Pre-made Cynomolgus/Rhesus macaque BRAF siRNA oligo Duplex693554Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092346Pre-made Cat/Feline BRAF siRNA oligo Duplex101092346Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo475526Pre-made Dog/Canine BRAF siRNA oligo Duplex475526Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo536051Pre-made Bovines/Cattle BRAF siRNA oligo Duplex536051Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100065760Pre-made Equine/Horse BRAF siRNA oligo Duplex100065760Equine/HorseIn-vitro grade; in-vivo gradeDetail


BRAF antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T99089-AbHumanAnti-Human BRAF monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T99089-AbRatAnti-Rat BRAF monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T99089-AbMouseAnti-Mouse BRAF monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T99089-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque BRAF monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T99089-AbCat/FelineAnti-Cat/Feline BRAF monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T99089-AbDog/CanineAnti-Dog/Canine BRAF monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T99089-AbBovines/CattleAnti-Bovines/Cattle BRAF monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T99089-AbEquine/HorseAnti-Equine/Horse BRAF monoclonal antibodymabTherapeutics Target antibodyDetail


BRAF recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T99089-AgHumanHuman BRAF recombinant proteinMammalian cellDetail
GM-Tg-rg-T99089-AgRatRat BRAF recombinant proteinMammalian cellDetail
GM-Tg-mg-T99089-AgMouseMouse BRAF recombinant proteinMammalian cellDetail
GM-Tg-cynog-T99089-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque BRAF recombinant proteinMammalian cellDetail
GM-Tg-felg-T99089-AgCat/FelineCat/Feline BRAF recombinant proteinMammalian cellDetail
GM-Tg-cang-T99089-AgDog/CanineDog/Canine BRAF recombinant proteinMammalian cellDetail
GM-Tg-bovg-T99089-AgBovines/CattleBovines/Cattle BRAF recombinant proteinMammalian cellDetail
GM-Tg-equg-T99089-AgEquine/HorseEquine/Horse BRAF recombinant proteinMammalian cellDetail