Explore RSPO1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
| Target ID |
GM-T91023
|
| Target Name |
RSPO1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
284654
|
| Gene ID |
100054745 (Equus caballus), 101091033 (Felis catus), 192199 (Mus musculus), 284654 (Homo sapiens)
313589 (Rattus norvegicus), 511675 (Bos taurus), 608179 (Canis lupus familiaris), 713976 (Macaca mulatta)
|
| Target Alternative Names |
CRISTIN3,R-spondin,R-spondin-1,RGD1565558,RSPO,RSPO1,Roof plate-specific spondin-1 (hRspo1),Rspo1,Rspondin
|
| Uniprot Accession |
Q9Z132,Q2MKA7
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Wnt signaling pathway
|
| Gene Ensembl |
ENSECAG00000022683, ENSMUSG00000028871, ENSG00000169218, ENSCAFG00845030653, ENSMMUG00000008420
|
Pre-made viral vector of RSPO1 cDNA Clones/ORF Plasmid
RSPO1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo284654 | Pre-made Human RSPO1/RSPO/CRISTIN3 siRNA oligo Duplex | 284654 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313589 | Pre-made Rat Rspo1/RGD1565558 siRNA oligo Duplex | 313589 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo192199 | Pre-made Mouse Rspo1/Rspondin/R-spondin siRNA oligo Duplex | 192199 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713976 | Pre-made Cynomolgus/Rhesus macaque RSPO1 siRNA oligo Duplex | 713976 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091033 | Pre-made Cat/Feline RSPO1 siRNA oligo Duplex | 101091033 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608179 | Pre-made Dog/Canine RSPO1 siRNA oligo Duplex | 608179 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511675 | Pre-made Bovines/Cattle RSPO1 siRNA oligo Duplex | 511675 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054745 | Pre-made Equine/Horse RSPO1 siRNA oligo Duplex | 100054745 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RSPO1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T91023-Ab | Human | Anti-Human RSPO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T91023-Ab | Rat | Anti-Rat RSPO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T91023-Ab | Mouse | Anti-Mouse RSPO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T91023-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RSPO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T91023-Ab | Cat/Feline | Anti-Cat/Feline RSPO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T91023-Ab | Dog/Canine | Anti-Dog/Canine RSPO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T91023-Ab | Bovines/Cattle | Anti-Bovines/Cattle RSPO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T91023-Ab | Equine/Horse | Anti-Equine/Horse RSPO1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
RSPO1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T91023-Ag | Human | Human RSPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T91023-Ag | Rat | Rat RSPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T91023-Ag | Mouse | Mouse RSPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T91023-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RSPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T91023-Ag | Cat/Feline | Cat/Feline RSPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T91023-Ag | Dog/Canine | Dog/Canine RSPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T91023-Ag | Bovines/Cattle | Bovines/Cattle RSPO1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T91023-Ag | Equine/Horse | Equine/Horse RSPO1 recombinant protein | Mammalian cell | Detail |
