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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Target ID |
GM-T89299
|
Target Name |
FOSL1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8061
|
Gene ID |
100051930 (Equus caballus), 101101337 (Felis catus), 106993191 (Macaca mulatta), 14283 (Mus musculus) 25445 (Rattus norvegicus), 483724 (Canis lupus familiaris), 531389 (Bos taurus), 8061 (Homo sapiens)
|
Target Alternative Names |
FOSL1,Fosl1,Fra1,fra-1,Fra-1,FRA,FRA1
|
Uniprot Accession |
P48755,P10158,P15407
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Therapeutics Target
|
Disease |
cancer
|
Disease from KEGG |
Wnt signaling pathway, Osteoclast differentiation, IL-17 signaling pathway, Human T-cell leukemia virus 1 infection
|
Gene Ensembl |
ENSECAG00000023092, ENSMMUG00000008653, ENSMUSG00000024912, ENSCAFG00845017398, ENSBTAG00000006194, ENSG00000175592
|
Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of FOSL1 cDNA Clones/ORF Plasmid
FOSL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo8061 | Pre-made Human FOSL1/FRA/FRA1 siRNA oligo Duplex | 8061 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo25445 | Pre-made Rat Fosl1/Fra-1/fra-1 siRNA oligo Duplex | 25445 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo14283 | Pre-made Mouse Fosl1/Fra1/fra-1 siRNA oligo Duplex | 14283 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo106993191 | Pre-made Cynomolgus/Rhesus macaque FOSL1 siRNA oligo Duplex | 106993191 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101101337 | Pre-made Cat/Feline FOSL1 siRNA oligo Duplex | 101101337 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo483724 | Pre-made Dog/Canine FOSL1 siRNA oligo Duplex | 483724 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo531389 | Pre-made Bovines/Cattle FOSL1 siRNA oligo Duplex | 531389 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100051930 | Pre-made Equine/Horse FOSL1 siRNA oligo Duplex | 100051930 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FOSL1 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T89299-Ab | Human | Anti-Human FOSL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-rg-T89299-Ab | Rat | Anti-Rat FOSL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-mg-T89299-Ab | Mouse | Anti-Mouse FOSL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cynog-T89299-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FOSL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-felg-T89299-Ab | Cat/Feline | Anti-Cat/Feline FOSL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cang-T89299-Ab | Dog/Canine | Anti-Dog/Canine FOSL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-bovg-T89299-Ab | Bovines/Cattle | Anti-Bovines/Cattle FOSL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-equg-T89299-Ab | Equine/Horse | Anti-Equine/Horse FOSL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
FOSL1 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T89299-Ag | Human | Human FOSL1 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T89299-Ag | Rat | Rat FOSL1 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T89299-Ag | Mouse | Mouse FOSL1 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T89299-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FOSL1 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T89299-Ag | Cat/Feline | Cat/Feline FOSL1 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T89299-Ag | Dog/Canine | Dog/Canine FOSL1 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T89299-Ag | Bovines/Cattle | Bovines/Cattle FOSL1 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T89299-Ag | Equine/Horse | Equine/Horse FOSL1 recombinant protein | Mammalian cell | Detail |