Explore CYP17A1/S17AH gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T89041
|
| Target Name |
CYP17A1/S17AH
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1586
|
| Gene ID |
100034232 (Equus caballus), 13074 (Mus musculus), 1586 (Homo sapiens), 25146 (Rattus norvegicus)
281739 (Bos taurus), 477807 (Canis lupus familiaris), 493967 (Felis catus), 678693 (Macaca mulatta)
|
| Target Alternative Names |
CYP17A1,Cyp17a1,P45017A1,Cyp17,p450c17,CPT7,CYP17,S17AH,P450C17,CYPXVII,P450c17,P450-C17
|
| Uniprot Accession |
Q95328,P27786,P05093,P11715,Q9GMC8,Q8HYM9
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Steroid hormone biosynthesis, Ovarian steroidogenesis, Prolactin signaling pathway, Cortisol synthesis and secretion, Cushing syndrome
|
| Gene Ensembl |
ENSECAG00000010022, ENSMUSG00000003555, ENSG00000148795, ENSBTAG00000064070, ENSCAFG00845025701, ENSMMUG00000017601
|
| Target Classification |
Tumor-associated antigen (TAA)
|
CYP17A1/S17AH siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1586 | Pre-made Human CYP17A1/CPT7/CYP17 siRNA oligo Duplex | 1586 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25146 | Pre-made Rat Cyp17a1/Cyp17 siRNA oligo Duplex | 25146 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13074 | Pre-made Mouse Cyp17a1/Cyp17/p450c17 siRNA oligo Duplex | 13074 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo678693 | Pre-made Cynomolgus/Rhesus macaque CYP17A1/CYP17 siRNA oligo Duplex | 678693 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493967 | Pre-made Cat/Feline CYP17A1/CYP17 siRNA oligo Duplex | 493967 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477807 | Pre-made Dog/Canine CYP17A1 siRNA oligo Duplex | 477807 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281739 | Pre-made Bovines/Cattle CYP17A1/CYP17/CYPXVII siRNA oligo Duplex | 281739 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034232 | Pre-made Equine/Horse CYP17A1/P45017A1 siRNA oligo Duplex | 100034232 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CYP17A1/S17AH antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T89041-Ab | Human | Anti-Human CYP17A1/S17AH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T89041-Ab | Rat | Anti-Rat CYP17A1/S17AH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T89041-Ab | Mouse | Anti-Mouse CYP17A1/S17AH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T89041-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CYP17A1/S17AH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T89041-Ab | Cat/Feline | Anti-Cat/Feline CYP17A1/S17AH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T89041-Ab | Dog/Canine | Anti-Dog/Canine CYP17A1/S17AH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T89041-Ab | Bovines/Cattle | Anti-Bovines/Cattle CYP17A1/S17AH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T89041-Ab | Equine/Horse | Anti-Equine/Horse CYP17A1/S17AH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CYP17A1/S17AH recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T89041-Ag | Human | Human CYP17A1/S17AH recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T89041-Ag | Rat | Rat CYP17A1/S17AH recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T89041-Ag | Mouse | Mouse CYP17A1/S17AH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T89041-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CYP17A1/S17AH recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T89041-Ag | Cat/Feline | Cat/Feline CYP17A1/S17AH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T89041-Ag | Dog/Canine | Dog/Canine CYP17A1/S17AH recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T89041-Ag | Bovines/Cattle | Bovines/Cattle CYP17A1/S17AH recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T89041-Ag | Equine/Horse | Equine/Horse CYP17A1/S17AH recombinant protein | Mammalian cell | Detail |
