Explore NPPC gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015]
| Target ID |
GM-T87689
|
| Target Name |
NPPC
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4880
|
| Gene ID |
100057178 (Equus caballus), 101097827 (Felis catus), 114593 (Rattus norvegicus), 18159 (Mus musculus)
281356 (Bos taurus), 4880 (Homo sapiens), 610169 (Canis lupus familiaris), 717026 (Macaca mulatta)
|
| Target Alternative Names |
C-type natriuretic peptide,CNP,CNP2,NPPC,Nppc,lbab
|
| Uniprot Accession |
P55207,Q61839,P55206,P23582
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000000840, ENSMUSG00000026241, ENSBTAG00000003253, ENSG00000163273, ENSCAFG00845024603, ENSMMUG00000006981
|
Pre-made viral vector of NPPC cDNA Clones/ORF Plasmid
NPPC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4880 | Pre-made Human NPPC/CNP/CNP2 siRNA oligo Duplex | 4880 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114593 | Pre-made Rat Nppc siRNA oligo Duplex | 114593 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18159 | Pre-made Mouse Nppc/CNP/lbab siRNA oligo Duplex | 18159 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717026 | Pre-made Cynomolgus/Rhesus macaque NPPC/CNP siRNA oligo Duplex | 717026 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097827 | Pre-made Cat/Feline NPPC siRNA oligo Duplex | 101097827 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610169 | Pre-made Dog/Canine NPPC siRNA oligo Duplex | 610169 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281356 | Pre-made Bovines/Cattle NPPC siRNA oligo Duplex | 281356 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057178 | Pre-made Equine/Horse NPPC siRNA oligo Duplex | 100057178 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NPPC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T87689-Ab | Human | Anti-Human NPPC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T87689-Ab | Rat | Anti-Rat NPPC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T87689-Ab | Mouse | Anti-Mouse NPPC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T87689-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NPPC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T87689-Ab | Cat/Feline | Anti-Cat/Feline NPPC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T87689-Ab | Dog/Canine | Anti-Dog/Canine NPPC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T87689-Ab | Bovines/Cattle | Anti-Bovines/Cattle NPPC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T87689-Ab | Equine/Horse | Anti-Equine/Horse NPPC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
NPPC recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T87689-Ag | Human | Human NPPC recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T87689-Ag | Rat | Rat NPPC recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T87689-Ag | Mouse | Mouse NPPC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T87689-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NPPC recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T87689-Ag | Cat/Feline | Cat/Feline NPPC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T87689-Ag | Dog/Canine | Dog/Canine NPPC recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T87689-Ag | Bovines/Cattle | Bovines/Cattle NPPC recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T87689-Ag | Equine/Horse | Equine/Horse NPPC recombinant protein | Mammalian cell | Detail |
