APP/Beta Amyloid Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore APP/Beta Amyloid gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]

Pre-made viral vector of APP/Beta Amyloid cDNA Clones/ORF Plasmid

APP/Beta Amyloid siRNA/miRNA/oligo for RNA interfence (RNAi)

APP/Beta Amyloid antibody/GMab

APP/Beta Amyloid VLP (virus-like particle)