Explore AQP3 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
| Target ID |
GM-T86226
|
| Target Name |
AQP3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
360
|
| Gene ID |
100053851 (Equus caballus), 101101676 (Felis catus), 11828 (Mus musculus), 360 (Homo sapiens) 611792 (Canis lupus familiaris), 65133 (Rattus norvegicus), 702721 (Macaca mulatta), 780866 (Bos taurus)
|
| Target Alternative Names |
AQP-2,AQP-3,AQP3,Aqp3,Aquaglyceroporin-3,Aquaporin-3,GIL
|
| Uniprot Accession |
Q8R2N1,Q92482,P47862,Q08DE6
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000021134, ENSMUSG00000028435, ENSG00000165272, ENSCAFG00845021223, ENSMMUG00000003314, ENSBTAG00000008493
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of AQP3 cDNA Clones/ORF Plasmid
AQP3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo360 | Pre-made Human AQP3/GIL/AQP-3 siRNA oligo Duplex | 360 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65133 | Pre-made Rat Aqp3 siRNA oligo Duplex | 65133 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11828 | Pre-made Mouse Aqp3/AQP-2 siRNA oligo Duplex | 11828 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702721 | Pre-made Cynomolgus/Rhesus macaque AQP3 siRNA oligo Duplex | 702721 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101676 | Pre-made Cat/Feline AQP3 siRNA oligo Duplex | 101101676 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611792 | Pre-made Dog/Canine AQP3 siRNA oligo Duplex | 611792 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo780866 | Pre-made Bovines/Cattle AQP3 siRNA oligo Duplex | 780866 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053851 | Pre-made Equine/Horse AQP3 siRNA oligo Duplex | 100053851 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AQP3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T86226-Ab | Human | Anti-Human AQP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T86226-Ab | Rat | Anti-Rat AQP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T86226-Ab | Mouse | Anti-Mouse AQP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T86226-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AQP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T86226-Ab | Cat/Feline | Anti-Cat/Feline AQP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T86226-Ab | Dog/Canine | Anti-Dog/Canine AQP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T86226-Ab | Bovines/Cattle | Anti-Bovines/Cattle AQP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T86226-Ab | Equine/Horse | Anti-Equine/Horse AQP3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
AQP3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T86226-Ag | Human | Human AQP3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T86226-Ag | Rat | Rat AQP3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T86226-Ag | Mouse | Mouse AQP3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T86226-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AQP3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T86226-Ag | Cat/Feline | Cat/Feline AQP3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T86226-Ag | Dog/Canine | Dog/Canine AQP3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T86226-Ag | Bovines/Cattle | Bovines/Cattle AQP3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T86226-Ag | Equine/Horse | Equine/Horse AQP3 VLP (virus-like particle) | HEK293 | Products Developing |