Explore NGF/beta NGF gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T85670
|
| Target Name |
NGF/beta NGF
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4803
|
| Gene ID |
100065669 (Equus caballus), 100144611 (Felis catus), 18049 (Mus musculus), 281350 (Bos taurus) 310738 (Rattus norvegicus), 403402 (Canis lupus familiaris), 4803 (Homo sapiens), 711681 (Macaca mulatta)
|
| Target Alternative Names |
Beta-NGF,Beta-nerve growth factor,HSAN5,NGF,NGFB,Ngf,Ngfb,beta NGF,beta-NGF
|
| Uniprot Accession |
P01139,P13600,P25427,P01138
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
Overactive bladder, Bladder Pain, Interstitial cystitis (chronic), Urinary Tract Infection, Neurological deficits - peripheral neuropathy, Parkinson's Disease
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels
|
| Gene Ensembl |
ENSECAG00000010553, ENSMUSG00000027859, ENSBTAG00000007446, ENSCAFG00845027859, ENSG00000134259
|
Pre-made viral vector of NGF/beta NGF cDNA Clones/ORF Plasmid
NGF/beta NGF siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4803 | Pre-made Human NGF/NGFB/HSAN5 siRNA oligo Duplex | 4803 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo310738 | Pre-made Rat Ngf/Ngfb/beta-NGF siRNA oligo Duplex | 310738 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18049 | Pre-made Mouse Ngf/Ngfb/beta-NGF siRNA oligo Duplex | 18049 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711681 | Pre-made Cynomolgus/Rhesus macaque NGF siRNA oligo Duplex | 711681 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100144611 | Pre-made Cat/Feline NGF/NGFB siRNA oligo Duplex | 100144611 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403402 | Pre-made Dog/Canine NGF/NGFB siRNA oligo Duplex | 403402 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281350 | Pre-made Bovines/Cattle NGF/NGFB siRNA oligo Duplex | 281350 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065669 | Pre-made Equine/Horse NGF/NGFB siRNA oligo Duplex | 100065669 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NGF/beta NGF antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85670-Ab | Human | Anti-Human NGF/beta NGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T85670-Ab | Rat | Anti-Rat NGF/beta NGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T85670-Ab | Mouse | Anti-Mouse NGF/beta NGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T85670-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NGF/beta NGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T85670-Ab | Cat/Feline | Anti-Cat/Feline NGF/beta NGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T85670-Ab | Dog/Canine | Anti-Dog/Canine NGF/beta NGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T85670-Ab | Bovines/Cattle | Anti-Bovines/Cattle NGF/beta NGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T85670-Ab | Equine/Horse | Anti-Equine/Horse NGF/beta NGF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
NGF/beta NGF recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85670-Ag | Human | Human NGF/beta NGF recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T85670-Ag | Rat | Rat NGF/beta NGF recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T85670-Ag | Mouse | Mouse NGF/beta NGF recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T85670-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NGF/beta NGF recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T85670-Ag | Cat/Feline | Cat/Feline NGF/beta NGF recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T85670-Ag | Dog/Canine | Dog/Canine NGF/beta NGF recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T85670-Ag | Bovines/Cattle | Bovines/Cattle NGF/beta NGF recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T85670-Ag | Equine/Horse | Equine/Horse NGF/beta NGF recombinant protein | Mammalian cell | Detail |