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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
| Target ID |
GM-T85616
|
| Target Name |
Thioredoxin/TXN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7295
|
| Gene ID |
100033827 (Equus caballus), 101090655 (Felis catus), 116484 (Rattus norvegicus), 22166 (Mus musculus)
280950 (Bos taurus), 474798 (Canis lupus familiaris), 712587 (Macaca mulatta), 7295 (Homo sapiens)
|
| Target Alternative Names |
TXN,Txn1,Txn,ADF,Trx1,Trx,TRX,TRDX,TRX1,TXN1,Trx80
|
| Uniprot Accession |
O97508,P11232,P10639,O97680,P99505,P29451,P10599
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
NOD-like receptor signaling pathway, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000013324, ENSMUSG00000028367, ENSBTAG00000002953, ENSCAFG00845013183, ENSMMUG00000052156, ENSG00000136810
|
| Target Classification |
|
Pre-made viral vector of Thioredoxin/TXN cDNA Clones/ORF Plasmid
Thioredoxin/TXN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7295 | Pre-made Human TXN/TRX/TRDX siRNA oligo Duplex | 7295 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116484 | Pre-made Rat Txn1/Txn siRNA oligo Duplex | 116484 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22166 | Pre-made Mouse Txn1/ADF/Txn siRNA oligo Duplex | 22166 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712587 | Pre-made Cynomolgus/Rhesus macaque TXN siRNA oligo Duplex | 712587 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090655 | Pre-made Cat/Feline TXN siRNA oligo Duplex | 101090655 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474798 | Pre-made Dog/Canine TXN/Trx siRNA oligo Duplex | 474798 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280950 | Pre-made Bovines/Cattle TXN siRNA oligo Duplex | 280950 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033827 | Pre-made Equine/Horse TXN siRNA oligo Duplex | 100033827 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Thioredoxin/TXN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85616-Ab | Human | Anti-Human Thioredoxin/TXN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T85616-Ab | Rat | Anti-Rat Thioredoxin/TXN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T85616-Ab | Mouse | Anti-Mouse Thioredoxin/TXN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T85616-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Thioredoxin/TXN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T85616-Ab | Cat/Feline | Anti-Cat/Feline Thioredoxin/TXN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T85616-Ab | Dog/Canine | Anti-Dog/Canine Thioredoxin/TXN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T85616-Ab | Bovines/Cattle | Anti-Bovines/Cattle Thioredoxin/TXN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T85616-Ab | Equine/Horse | Anti-Equine/Horse Thioredoxin/TXN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Thioredoxin/TXN recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85616-Ag | Human | Human Thioredoxin/TXN recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T85616-Ag | Rat | Rat Thioredoxin/TXN recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T85616-Ag | Mouse | Mouse Thioredoxin/TXN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T85616-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Thioredoxin/TXN recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T85616-Ag | Cat/Feline | Cat/Feline Thioredoxin/TXN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T85616-Ag | Dog/Canine | Dog/Canine Thioredoxin/TXN recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T85616-Ag | Bovines/Cattle | Bovines/Cattle Thioredoxin/TXN recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T85616-Ag | Equine/Horse | Equine/Horse Thioredoxin/TXN recombinant protein | Mammalian cell | Detail |
