Explore CD28 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
| Target ID |
GM-T85529
|
| Target Name |
CD28
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
940
|
| Gene ID |
100067829 (Equus caballus), 12487 (Mus musculus), 25660 (Rattus norvegicus), 281050 (Bos taurus)
403646 (Canis lupus familiaris), 493802 (Felis catus), 705313 (Macaca mulatta), 940 (Homo sapiens)
|
| Target Alternative Names |
CD28,CD28RNA,Cd28,IMD123,T-cell-specific surface glycoprotein CD28,TP44,Tp44
|
| Uniprot Accession |
P31041,P31042,Q28071,O02757,P10747
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Cell adhesion molecules, T cell receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Autoimmune thyroid disease, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis
|
| Gene Ensembl |
ENSECAG00000022853, ENSMUSG00000026012, ENSBTAG00000007445, ENSCAFG00845018097, ENSMMUG00000057214, ENSG00000178562
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CD28 cDNA Clones/ORF Plasmid
CD28 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo940 | Pre-made Human CD28/Tp44/IMD123 siRNA oligo Duplex | 940 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25660 | Pre-made Rat Cd28/CD28RNA siRNA oligo Duplex | 25660 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12487 | Pre-made Mouse Cd28 siRNA oligo Duplex | 12487 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705313 | Pre-made Cynomolgus/Rhesus macaque CD28 siRNA oligo Duplex | 705313 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493802 | Pre-made Cat/Feline CD28 siRNA oligo Duplex | 493802 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403646 | Pre-made Dog/Canine CD28 siRNA oligo Duplex | 403646 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281050 | Pre-made Bovines/Cattle CD28 siRNA oligo Duplex | 281050 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067829 | Pre-made Equine/Horse CD28 siRNA oligo Duplex | 100067829 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD28 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85529-Ab | Human | Anti-Human CD28 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T85529-Ab | Rat | Anti-Rat CD28 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T85529-Ab | Mouse | Anti-Mouse CD28 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T85529-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD28 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T85529-Ab | Cat/Feline | Anti-Cat/Feline CD28 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T85529-Ab | Dog/Canine | Anti-Dog/Canine CD28 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T85529-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD28 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T85529-Ab | Equine/Horse | Anti-Equine/Horse CD28 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD28 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85529-Ag | Human | Human CD28 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T85529-Ag | Rat | Rat CD28 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T85529-Ag | Mouse | Mouse CD28 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T85529-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD28 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T85529-Ag | Cat/Feline | Cat/Feline CD28 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T85529-Ag | Dog/Canine | Dog/Canine CD28 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T85529-Ag | Bovines/Cattle | Bovines/Cattle CD28 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T85529-Ag | Equine/Horse | Equine/Horse CD28 VLP (virus-like particle) | HEK293 | Products Developing |
