SIRT2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SIRT2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]

Target ID	GM-T83904
Target Name	SIRT2
Gene Group ldentifer （Target Gene ID in Homo species)	22933
Gene ID	100146611 (Equus caballus), 100425019 (Macaca mulatta), 101099513 (Felis catus), 22933 (Homo sapiens) 361532 (Rattus norvegicus), 504463 (Bos taurus), 612558 (Canis lupus familiaris), 64383 (Mus musculus)
Target Alternative Names	5730427M03Rik,NAD-dependent protein deacetylase sirtuin-2,NAD-dependent protein defatty-acylase sirtuin-2,Regulatory protein SIR2 homolog 2,SIR2,SIR2-like protein 2,SIR2L,SIR2L2,SIRT2,Sir2l,Sirt2
Uniprot Accession	Q8IXJ6,Q5RJQ4,Q8VDQ8
Protein Sub-location	Introcelluar Protein
Category	Therapeutics Target
Disease from KEGG	Metabolic pathways
Gene Ensembl	ENSECAG00000023223, ENSMMUG00000023640, ENSG00000068903, ENSBTAG00000001776, ENSCAFG00845004895, ENSMUSG00000015149

Pre-made viral vector of SIRT2 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP001425	Human SIRT2/SIR2/SIR2L Lentivirus plasmid	NM_012237	22933	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMPC000307	Human SIRT2/SIR2/SIR2L Mammalian (Non-Viral Vector) plasmid	NM_012237	22933	Human	Mammalian (Non-Viral Vector) plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMPC000562	Human SIRT2/SIR2/SIR2L Mammalian (Non-Viral Vector) plasmid	NM_012237.4	22933	Human	Mammalian (Non-Viral Vector) plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMPC001357	Human SIRT2/SIR2/SIR2L Mammalian (Non-Viral Vector) plasmid	NM_012237.4	22933	Human	Mammalian (Non-Viral Vector) plasmid	Null	3xflag (C-Terminal)	CMV	Detail
vGMLP001425	Human SIRT2/SIR2/SIR2L Lentivirus particle	NM_012237	22933	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAAV001626	Rat Sirt2 Adeno-associate virus(AAV) plasmid	NM_001399630.1	361532	Rat	Adeno-associate virus(AAV) plasmid	ZsGreen	Null	CMV	Detail
vGMAAV001626	Rat Sirt2 Adeno-associate virus(AAV) particle	NM_001399630.1	361532	Rat	Adeno-associate virus(AAV) particle	ZsGreen	Null	CMV	Detail
pGMAD001591	Mouse Sirt2/5730427M03Rik/Sir2l Adenovirus plasmid	NM_022432.5	64383	Mouse	Adenovirus plasmid	Firefly luciferase	3xflag (C-Terminal)	EF1	Detail
pGMAAV001227	Mouse Sirt2/5730427M03Rik/Sir2l Adeno-associate virus(AAV) plasmid	NM_022432	64383	Mouse	Adeno-associate virus(AAV) plasmid	Firefly luciferase	3xflag (C-Terminal)	TBG	Detail
pGMLPm001847	Mouse Sirt2/5730427M03Rik/Sir2l Lentivirus plasmid	NM_022432	64383	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAD001591	Mouse Sirt2/5730427M03Rik/Sir2l Adenovirus particle	NM_022432.5	64383	Mouse	Adenovirus particle	Firefly luciferase	3xflag (C-Terminal)	EF1	Detail
vGMAAV001227	Mouse Sirt2/5730427M03Rik/Sir2l Adeno-associate virus(AAV) particle	NM_022432	64383	Mouse	Adeno-associate virus(AAV) particle	Firefly luciferase	3xflag (C-Terminal)	TBG	Detail
vGMLPm001847	Mouse Sirt2/5730427M03Rik/Sir2l Lentivirus particle	NM_022432	64383	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

SIRT2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo22933	Pre-made Human SIRT2/SIR2/SIR2L siRNA oligo Duplex	22933	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo361532	Pre-made Rat Sirt2 siRNA oligo Duplex	361532	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo64383	Pre-made Mouse Sirt2/Sir2l/SIR2L2 siRNA oligo Duplex	64383	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo100425019	Pre-made Cynomolgus/Rhesus macaque SIRT2 siRNA oligo Duplex	100425019	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101099513	Pre-made Cat/Feline SIRT2 siRNA oligo Duplex	101099513	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo612558	Pre-made Dog/Canine SIRT2 siRNA oligo Duplex	612558	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo504463	Pre-made Bovines/Cattle SIRT2 siRNA oligo Duplex	504463	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100146611	Pre-made Equine/Horse SIRT2 siRNA oligo Duplex	100146611	Equine/Horse	In-vitro grade; in-vivo grade	Detail

SIRT2 antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T83904-Ab	Human	Anti-Human SIRT2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-rg-T83904-Ab	Rat	Anti-Rat SIRT2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-mg-T83904-Ab	Mouse	Anti-Mouse SIRT2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cynog-T83904-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque SIRT2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-felg-T83904-Ab	Cat/Feline	Anti-Cat/Feline SIRT2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cang-T83904-Ab	Dog/Canine	Anti-Dog/Canine SIRT2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-bovg-T83904-Ab	Bovines/Cattle	Anti-Bovines/Cattle SIRT2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-equg-T83904-Ab	Equine/Horse	Anti-Equine/Horse SIRT2 monoclonal antibody	mab	Therapeutics Target antibody	Detail

SIRT2 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T83904-Ag	Human	Human SIRT2 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T83904-Ag	Rat	Rat SIRT2 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T83904-Ag	Mouse	Mouse SIRT2 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T83904-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque SIRT2 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T83904-Ag	Cat/Feline	Cat/Feline SIRT2 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T83904-Ag	Dog/Canine	Dog/Canine SIRT2 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T83904-Ag	Bovines/Cattle	Bovines/Cattle SIRT2 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T83904-Ag	Equine/Horse	Equine/Horse SIRT2 recombinant protein	Mammalian cell	Detail