Explore FOLR1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
| Target ID |
GM-T83386
|
| Target Name |
FOLR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2348
|
| Gene ID |
100066084 (Equus caballus), 101084221 (Felis catus), 14275 (Mus musculus), 171049 (Rattus norvegicus)
2348 (Homo sapiens), 539750 (Bos taurus), 718388 (Macaca mulatta)
|
| Target Alternative Names |
Adult folate-binding protein (FBP),FBP,FBP1,FOLR,FOLR1,FR-alpha,FRalpha,Fbp1,Folate receptor,Folate receptor 1,Folate receptor alpha,Folbp-1,Folbp1,Folr1,KB cells FBP,NCFTD,Ovarian tumor-associated antigen MOv18,adult
|
| Uniprot Accession |
P35846,P15328
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer, Ovary Cancer
|
| Disease from KEGG |
Antifolate resistance
|
| Gene Ensembl |
ENSECAG00000020411, ENSMUSG00000001827, ENSG00000110195, ENSBTAG00000021007, ENSMMUG00000010455
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of FOLR1 cDNA Clones/ORF Plasmid
FOLR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2348 | Pre-made Human FOLR1/FBP/FOLR siRNA oligo Duplex | 2348 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171049 | Pre-made Rat Folr1/Fbp1 siRNA oligo Duplex | 171049 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14275 | Pre-made Mouse Folr1/FBP1/Folbp1 siRNA oligo Duplex | 14275 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718388 | Pre-made Cynomolgus/Rhesus macaque FOLR1 siRNA oligo Duplex | 718388 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084221 | Pre-made Cat/Feline FOLR1 siRNA oligo Duplex | 101084221 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539750 | Pre-made Bovines/Cattle FOLR1 siRNA oligo Duplex | 539750 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066084 | Pre-made Equine/Horse FOLR1 siRNA oligo Duplex | 100066084 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FOLR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T83386-Ab | Human | Anti-Human FOLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T83386-Ab | Rat | Anti-Rat FOLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T83386-Ab | Mouse | Anti-Mouse FOLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T83386-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FOLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T83386-Ab | Cat/Feline | Anti-Cat/Feline FOLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T83386-Ab | Bovines/Cattle | Anti-Bovines/Cattle FOLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T83386-Ab | Equine/Horse | Anti-Equine/Horse FOLR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
FOLR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T83386-Ag | Human | Human FOLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T83386-Ag | Rat | Rat FOLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T83386-Ag | Mouse | Mouse FOLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T83386-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FOLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T83386-Ag | Cat/Feline | Cat/Feline FOLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T83386-Ag | Bovines/Cattle | Bovines/Cattle FOLR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T83386-Ag | Equine/Horse | Equine/Horse FOLR1 VLP (virus-like particle) | HEK293 | Products Developing |
