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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
| Target ID |
GM-T81903
|
| Target Name |
OSCAR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
126014
|
| Gene ID |
100051988 (Equus caballus), 100336423 (Bos taurus), 105261216 (Felis catus), 106994857 (Macaca mulatta)
126014 (Homo sapiens), 232790 (Mus musculus), 292537 (Rattus norvegicus), 484313 (Canis lupus familiaris)
|
| Target Alternative Names |
OSCAR,Oscar,PIGR3,PIgR-3,mOSCAR,mOSCAR-M1,mOSCAR-M2,mOSCAR-M3,RGD1559897
|
| Uniprot Accession |
Q8IYS5,Q8VBT3
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Osteoclast differentiation
|
| Gene Ensembl |
ENSECAG00000039917, ENSBTAG00000001051, ENSG00000170909, ENSMUSG00000054594
|
| Target Classification |
|
Pre-made viral vector of OSCAR cDNA Clones/ORF Plasmid
OSCAR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo126014 | Pre-made Human OSCAR/PIGR3/PIgR-3 siRNA oligo Duplex | 126014 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292537 | Pre-made Rat Oscar/RGD1559897 siRNA oligo Duplex | 292537 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo232790 | Pre-made Mouse Oscar/mOSCAR/mOSCAR-M1 siRNA oligo Duplex | 232790 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106994857 | Pre-made Cynomolgus/Rhesus macaque OSCAR siRNA oligo Duplex | 106994857 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo105261216 | Pre-made Cat/Feline OSCAR siRNA oligo Duplex | 105261216 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484313 | Pre-made Dog/Canine OSCAR siRNA oligo Duplex | 484313 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100336423 | Pre-made Bovines/Cattle OSCAR siRNA oligo Duplex | 100336423 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051988 | Pre-made Equine/Horse OSCAR siRNA oligo Duplex | 100051988 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OSCAR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T81903-Ab | Human | Anti-Human OSCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T81903-Ab | Rat | Anti-Rat OSCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T81903-Ab | Mouse | Anti-Mouse OSCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T81903-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OSCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T81903-Ab | Cat/Feline | Anti-Cat/Feline OSCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T81903-Ab | Dog/Canine | Anti-Dog/Canine OSCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T81903-Ab | Bovines/Cattle | Anti-Bovines/Cattle OSCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T81903-Ab | Equine/Horse | Anti-Equine/Horse OSCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
OSCAR VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T81903-Ag | Human | Human OSCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T81903-Ag | Rat | Rat OSCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T81903-Ag | Mouse | Mouse OSCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T81903-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OSCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T81903-Ag | Cat/Feline | Cat/Feline OSCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T81903-Ag | Dog/Canine | Dog/Canine OSCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T81903-Ag | Bovines/Cattle | Bovines/Cattle OSCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T81903-Ag | Equine/Horse | Equine/Horse OSCAR VLP (virus-like particle) | HEK293 | Products Developing |
